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STEP 1 Qbank Flash Cards > Autoantibodies > Flashcards

Autoantibodies Flashcards

1
Q

Anti-ACh receptor

A

Myasthenia Gravis

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2
Q

Anti-GBM

A

Goodpasture syndrome

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3
Q

Anti-beta2 glycoprotein

A

Antiphospholipid syndrome

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4
Q

Anticardiolipin

A

SLE, antiphospholipid syndrome

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5
Q

Anticentromere

A

Limited scleroderma (CREST)

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6
Q

Anti-desmoglein

A

Pemphigus vulgaris

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7
Q

Anti-glutamic acid decarboxylase

A

Type I diabetes

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8
Q

Anti-hemidesmosome

A

Bullous pemphigoid

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9
Q

Antisynthetase (eg anti-Jo-1), anti-SRP, anti-helicase (anti-Mi-2)

A

Polymyositis, dermatomyositis

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10
Q

Antimitochondrial

A

1° biliary sclerosis (PBC)

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11
Q

Antiparietal cell, anti-intrinsic factor

A

Pernicious anemia

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12
Q

Antiphospholipase A2 receptor

A

1° membranous nephropathy

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13
Q

Anti-Scl70 (anti-DNA topoisomerase)

A

Diffuse scleroderma

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14
Q

Anti-smooth muscle

A

Autoimmune hepatitis type 1

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15
Q

Anti-SSA, Anti-SSB (anti-Ro, anti-La)

A

Sjögren Syndrome

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16
Q

Anti-TSH receptor

A

Graves Disease

17
Q

Anti-presynaptic voltage-gated calcium channel

A

Lambert-Eaton myasthenic syndrome

18
Q

IgA anti-endomysial, IgA anti-TTG

A

Celiac disease

19
Q

MPO-ANCA/p-ANCA

A

Microscopic polyangitis, eosinophilic granulomatosis with polyangitis (Churg-Strauss), ulcerative colitis

20
Q

PR3-ANCA/c-ANCA

A

Granulomatosis with polyangitis (Wegener)

21
Q

Rheumatoid factor

A

Rheumatoid arthritis

22
Q

Anti-CCP

A

More specific marker of rheumatoid arthritis

23
Q

Antinuclear (ANA)

A

Nonspecific; often associated with SLE

24
Q

Anti-dsDNA

25
Q

Anti-Smith

26
Q

Anti-histone

A

Drug-induced lupus

27
Q

Anti-U1 RNP

A

Mixed connective tissue disease

STEP 1 Qbank Flash Cards (6 decks)

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