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Step 1- Immunology > Autoantibodies > Flashcards

Autoantibodies Flashcards

1
Q

anti-AChR

A

myasthenia gravis

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2
Q

anti-basement membrane

A

Goodpasture

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3
Q

anticardiolipin, lupus anticoagulant

A

SLE, antiphospholipid syndrome

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4
Q

anticentromere

A

limited scleroderma (CREST syndrome)

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5
Q

andi-desmosome (anti-desmoglein)

A

pemphigus vulgaris

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6
Q

anti-dsDNA, anti-Smith

A

SLE

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7
Q

anti-glutamic acid decarboxylase (GAD-65)

A

type I DM

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8
Q

antihemidesmosome

A

bullous pemphigoid

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9
Q

anti-histone

A

drug-induced lupus

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10
Q

anti Jo 1

A

polymyositis, dermatomyositis

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11
Q

antimicrosomal

A

Hashimoto thyroiditis

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12
Q

antimitochondrial

A

primary biliary cirrhosis

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13
Q

antinuclear antibodies

A

SLE, nonspecific

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14
Q

antiparietal cell

A

pernicious anemia

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15
Q

anti-Scl-70 (anti-DNA topoisomerase I)

A

scleroderma (diffuse)

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16
Q

anti-smooth muscle

A

autoimmune hepatitis

17
Q

anti-SSA, anti-SSB (anti-Ro, anti-La)

A

Sjogren syndrome

18
Q

anti-TSH receptor

A

Graves disease

19
Q

anti-U1 RNP (ribonucleoprotein)

A

MCTD

20
Q

IgA anti-endomysial, IgA anti-tissue transglutaminase

A

celiac disease

21
Q

MPO-ANCA/p-ANCA

A

microscopic polyangiitis, eosinophilic granulomatosis with polyangiitis (Churg Strauss syndrome )

22
Q

PR3-ANCA/c-ANCA

A

granulomatosis with polyangiitis (Wegener)

23
Q

rhuematoid factor (IgM antibody that targets IgG Fc region)

A

rheumatoid arthritis

24
Q

anti-CCP (more specific)

A

rheumatoid arthritis

25
Q

anti-SRP

A

dermatomyositis, polymyositis

26
Q

anti Mi 2

A

dermatomyositis, polymyositis

27
Q

antithyroglobulin

A

Hashimoto thyroiditis

Step 1- Immunology (5 decks)

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