Autoantibodies **** Flashcards

1
Q

Myasthenia gravis auto-antibody

A

Anti-ACh receptor

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2
Q

Goodpasture syndrome auto-antibody

A

Anti-basement membrane

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3
Q

SLE, antiphospholipid syndrome auto-antibody

A

Anti-cardiolipin, lupus anticoagulant

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4
Q

Limited scleroderma/CREST auto-antibody

A

Anti-centromere

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5
Q

Pemphigus vulgaris auto-antibody

A

Anti-desmoglein

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6
Q

SLE auto-antibody

A

Anti-dsDNA, anti-Smith

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7
Q

Type 1 DM

A

Anti-glutamate decarboxylase

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8
Q

Bullous pemphigoid

A

Anti-hemidesmosome

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9
Q

Drug-induced lupus

A

Antihistone

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10
Q

Polymyositis, dermatomyositis

A

Anti-Jo-1, anti-SRP, anti-Mi-2

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11
Q

Hashimoto thyroiditis

A

Antimicrosomal, antithyroglobulin

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12
Q

Primary biliary cirrhosis

A

Antimitochondrial

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13
Q

SLE, nonspecific

A

antinuclear antibodies

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14
Q

Diffuse scleroderma

A

Anti-Scl-70

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15
Q

Autoimmune hepatitis

A

Anti-smooth muscle

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16
Q

Sjogren syndrome

A

Anti-SSA, Anti-SSB (anti-Ro, anti-La)

17
Q

Graves disease

A

anti-TSH

18
Q

Mixed connective tissue disease

A

Anti-U1 RNP

19
Q

GPA (Wegener)

A

c-ANCA

20
Q

Celiac disease

A

IgA antiendomysial, IgA anti-tissue transglutaminase

21
Q

Microscopic polyangiitis, Churg-Strauss

A

p-ANCA

22
Q

Rheumatoid arthritis

A

RF (antibody, mostly IgM, specific to IgG Fc region), anti-CCP