Autoantibodies Flashcards

1
Q

ANA

A

SLE, nonspecific

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2
Q

Anti-dsDNA

A

SLE

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3
Q

Anti-Ro

A

Sjogren’s syndrome

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4
Q

Anti-La

A

Sjogren’s syndrome

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5
Q

Anti-Smith

A

SLE

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6
Q

Anti-nRNP/anti-U1-RNP (ribonucleotide protein)

A

Mixed connective tissue disease

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7
Q

Anti-SCL-70

A

Scleroderma (diffuse)

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8
Q

Anti-Jo-1

A

Polymyositis, dermatomyositis

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9
Q

Anti-histone

A

Drug-induced lupus

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10
Q

Anti-centromere

A

Scleroderma (CREST syndrome)

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11
Q

Anti-p62

A

Primary biliary cirrhosis

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12
Q

Anti-sp100

A

Primary biliary cirrhosis

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13
Q

Rheumatoid factor

A

Rheumatoid Arthritis

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14
Q

Anti-smooth muscle antibody

A

Autoimmune hepatitis

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15
Q

Anti-mitochondrial antibody

A

Primary Biliary Cirrhosis

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16
Q

Anti-SRP

A

Polymyositis, dermatomyositis

17
Q

Anti-CCP

A

Rheumatoid Arthritis

18
Q

IgA anti-tissue transglutaminase (tTG)

A

Celiac Disease

19
Q

Anti-epidermal transglutaminase (eTG)

A

Dermatitis herpetiformis (associated with Celiac disease)

20
Q

Anti-actin

A

Autoimmune hepatitis

21
Q

cANCA (PR3-ANCA)

A

Granulomatosis with polyangiitis (Wegner’s)

22
Q

pANCA (MPO-ANCA)

A

Microscopic polyangiitis, Churg-Strauss syndrome

23
Q

Anti-nicotinic acetylcholine receptor

A

Myasthenia Gravis

24
Q

Anti-VGKC (voltage gated potassium channels)

A

Morvan’s syndrome

25
Q

Anti-thyroid peroxidase (TPO)

A

Hashimoto’s thyroiditis

26
Q

Anti-TSH receptor

A

Grave’s Disease

27
Q

Anti-IgG Ab

A

Rheumatoid Arthritis

28
Q

anti-DNA topoisomerase I

A

Scleroderma (diffuse)

29
Q

IgA antiendomysial

A

Celiac Disease

30
Q

Anti-basement membrane

A

Goodpasture’s syndrome

31
Q

Anti-desmoglein

A

Pemphigus vulgaris

32
Q

Anti-microsomal

A

Hashimoto’s thyroiditis

33
Q

Anti-thyroglobulin

A

Hashimoto’s thyroiditis

34
Q

Anti-SSA (Ro)

A

Sjogren’s syndrome

35
Q

Anti-SSB (La)

A

Sjogren’s syndrome

36
Q

Anti-glutamate decarboxylase

A

Type 1 DM

37
Q

Anti-hemidesmosomes

A

Bullous pemphigoid

38
Q

Anti-presynaptic calcium channels Ab with small cell lung CA

A

Lambert-Eaton Syndrome