Autoantibodies Flashcards
Anti-dsDNA and Anti-smith
Specific for SLE
Initial antibody for SLE
ANA
Anti histone antibody is specific for…
Drug-induced lupus (e.g. Hydralazine)
Anti-scl70 is specific for
Systemic sclerosis
Anti-centromere is specific for
Limited sclerosis/CREST syndrome
Anti-Jo1 is specific for..
Polymyositis
Anti-Ro, Anti-La are specific for..
Sjogren’s disease
Anti-mitochondrial antibody is specific for…
Primary biliary cirrhosis
Anti-smooth muscle antibodies
Autoimmune hepatitis
pANCA is specific for
Churg Strauss (Eosinophilic
Granulomatosis with Polyangiitis)
cANCA is specific for
Wegener’s Granulomatosis
(Granulomatosis with Polyangiitis)
Anti-tissue transglutaminase and IgA,
Anti-gliadin, Anti-endomysial
Are specific for
Celiac disease