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Emily Pathology > Autoantibodies > Flashcards

Autoantibodies Flashcards

1
Q

Antiphospholipid syndrome

A

Anti cardiolipin

Anti B2 glycoprotein

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2
Q

Autoimmune hepatitis

A

Anti smooth muscle
Anti liver kidney microsomal 1 (Anti LKM-1)
Anti soluble liver antigen (anti SLA)

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3
Q

Autoimmune Haemolytic Anaemia

A

Anti Rh blood group antigen

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4
Q

Autoimmune thrombocytopenic purpura

A

Anti glycoprotein IIb/IIIa

Anti glycoprotein Ib/IX

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5
Q

Churg-Strauss Syndrome (EGPA = eosinophilic granulomatosis with polyangitis)

A

P-ANCA angainst MPO

Perinuclear ANCA against myeloperoxidase

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6
Q

Coeliac disease

A

Anti TTG

anti EMA

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7
Q

Dermatitis Herpetiformis

A

Anti endomysial antibody (EMA)

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8
Q

Dermatomyositis

A

Anti-jo-1 (t rna synthetase)

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9
Q

Diffuse cutaneous scleroderma

A

Anti topoisomerase/Scl70

Anti RNA pol I / II / III

anti fibrillarin

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10
Q

Good pastures syndrome

A

Anti GBM (glomerular basement membrane)

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11
Q

Graves’ disease

A

Anti TSH receptor

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12
Q

Hashimoto’s thyroiditis

A

Anti thyroglobulin

Anti thyroperoxidase

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13
Q

CREST or limited cutaneous scleroderma

A

Anti centromere

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14
Q

Microscopic polyangitis

A

P-ANCA

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15
Q

Mixed connective tissue disease

A

Anti U1RNP

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16
Q

Myasthenia gravis

A

Anti ach receptor

17
Q

Pernicious anaemia

A

Anti gastric parietal cells

Anti intrinsic factor

18
Q

Polymyositis

A

Anti Jo 1

19
Q

Primary biliary cirrhosis

A

Anti mitochondrial

20
Q

Rheumatoid arthritis

A

anti CCP

anti rheumatoid factor

21
Q

Sjögren’s syndrome

A

Anti ro
Anti la
Rheumatoid factor

22
Q

SLE

A 
anti dsDNA+ histones
Anti ro
Anti la
Anti SM
Anti U1RNP
23
Q

T1DM

A

Anti glutamate decarboxylase

Anti pancreatic Beta cells

24
Q

Wegeners granulomatosis

A

c-ANCA

25
Q

Target of p ANCA

A

Myeloperoxidase

26
Q

Target of p anca

A

Myeloperoxidase

27
Q

Target of c anca

A

Proteinase 3

28
Q

Congenital heart block in SLE

A

Anti ro

Emily Pathology (6 decks)

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