Auto immune 1-6

Question 1

what is meant by rheumatoid arthritis?

Answer 1

Rheumatoid arthritis is a long-term autoimmune condition that causes pain, swelling and stiffness in the joints.

Question 2

what are the pharmacists job if suspects someone who have RA

Answer 2

• Identification of possible RA and referral to GP- the earlier you can get it into remission the less likelihood of getting joint damage
• Management of RA therapy to minimise disease flare ups
• Management of therapy complications -typically you see it happen locally but can occur throughout the body.

Question 3

what other considerations would you have to take into consideration for RA?

Answer 3

• Age
• Gender
• Current drug therapy
• Side effects to ensure maximum adherence

Question 4

what is meant by the innate adaptive immunity

Answer 4

• The innate system works immediately when a problem has been detected.
• For example when a bacteria gets past the epithelial cells a series of cells becomes activated. Myeloid cells, neutrophils mast cells, phagocytic cells and cells which will recognise the microbes to t-cells
• There are secretary components such as cytokines which complement natural antibodies
• The production of cytokines and the involvement in these myeloid cells cause inflammation
• There will be a dispersants in response to the infection protective against specific pathogens
• Your innate immune system tries to contain an infection. if it can’t be contained we adapt the immune system occurs. Dendritic cells break down the microbes presented on naïve t cells which proliferates to effect the cells.
• They also signal b cells from to produce specific antibodies