Auto-Antibodies

Question 1

Anti-CCP antibodies

Answer 1

Rheumatoid arthritis

Question 2

Anti-nuclear antibody (ANA)

Answer 2

SLE
Sjogrens syndrome
Systemic sclerosis
MCTD (mixed connective tissue disease)
Autoimmune liver disease

Question 3

Anti double stranded DNA antibody (dsDNA)

Answer 3

SLE

Question 4

Anti-Sm (smooth muscle)

Answer 4

SLE

Question 5

Anti-Ro

Answer 5

SLE

Sjogrens syndrome

Question 6

Anti-La

Answer 6

Sjogrens syndrome

Question 7

Anti-centromere antibody

Answer 7

Systemic sclerosis (limited)

Question 8

Anti-Scl-70 antibody

Answer 8

Systemic sclerosis (diffuse)

Question 9

Anti-RNP antibody

Answer 9

SLE

MCTD (mixed connective tissue disease)

Question 10

Anti-Jo-1 antibody

Answer 10

Myositis

Question 11

Anti cardiolipin antibody + lupus anticoagulant

Answer 11

Anti-phospholipid syndrome

Question 12

Anti-neutrophil cytoplasmic antibody (ANCA)

Answer 12

Small vessel vasculitis (GPA, EGPA, MPA)

Question 13

Rheumatoid arthritis

Answer 13

Anti-CCP antibodies

Rheumatoid factor

Question 14

SLE

Answer 14

Anti-nuclear antibody (ANA)
Anti-dsDNA
Anti-Sm
Anti-Ro
Anti-RNP

Question 15

Sjogrens syndrome

Answer 15

ANA
Anti-Ro
Anti-La

Question 16

Systemic sclerosis (limited/diffuse)

Answer 16

ANA
Anti-centromere –> limited
Anti-Scl-70 –> diffuse

Question 17

Mixed connective tissue disease

Answer 17

ANA

Anti-RNP

Question 18

Autoimmune liver disease

Answer 18

ANA

Question 19

Myositis

Answer 19

Anti-Jo-1

Question 20

Anti-phospholipid syndrome

Answer 20

Anti cardiolipin antibody + lupus anticoagulant

Question 21

Small vessel vasculitis (GPA, EGPA, MPA)

Answer 21

Anti-neutrophil cytoplasmic antibody (ANCA)