Auto antibodies Flashcards

1
Q

Anti-Ach receptor

A

Myasthenia

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2
Q

Anti-basement membrane

A

Goodpasture

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3
Q

Anti-cardiolipin

A

SLE, antiphospholipid

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4
Q

Anticentromere

A

CREST

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5
Q

Anti-desmoglein

A

Pemphigus

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6
Q

Anti-ds DNA

A

SLE

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7
Q

Anti-glutamate decarboxylase

A

Type 1 DM

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8
Q

Anti-hemidesmosome

A

Bullous pemphigoid

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9
Q

Antihistone

A

Drug-induced lupus

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10
Q

Anti-Jo, Anti-Mi, Anti-SRP (anti-histidyl-tRNA synthetase)

A

Polymyositis, dermatomyositis

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11
Q

antimicrosomal, antithyroglbulin

A

hashimoto

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12
Q

Antimitchondrial

A

primary biliary cirrhosis

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13
Q

Anti DNA topoisomerase 1

A

Scleroderma (Anti-Scl-70)

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14
Q

Anti-smooth muscle

A

Autoimmune hepatitis

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15
Q

Anti-Ro, Anti-La (anti-nuclear)

A

Sjogren

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16
Q

Anti-TSH

A

Graves

17
Q

Anti ribonucleoprotein

A

Mixed connective tissue disease - SLE + CREST + Polymyositis

18
Q

IgA antiendomysial, anti-transglutaminase

A

Celiac

19
Q

PR3-ANCA

A

Granulomatosis with polyangiitis

20
Q

MPO-ANCA

A

Microscopic polyangiitis, churg-strauss

21
Q

IgM to Fc of IgG, anti-CCP

A

Rheumatoid

22
Q

Lupus anticoagulant

A

Antiphospholipid syndrome - Elevated PTT w/increased clotting and spontaneous abortions - False positive VDRL

Rx: Anticoagulate patient