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AU14 - Pharm Exam 3 > au14_-_pharmacology_exam_3_20141210195121 > Flashcards

au14_-_pharmacology_exam_3_20141210195121 Flashcards

1
Q

causes agranulocytosis

A

ticlopidine

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2
Q

causes altered color vision

A
  • qunidine- digoxin (yellow/green tinted)- sildenafil, vardenafil, tadalafil, avanafil, alprostadil (impaired blue/green color discrimination)
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3
Q

causes altered eye conditions

A
  • amiodarone (corneal deposits (optic neuritis)- sildenafil, vardenafil, tadalafil, avanafil, alprostadil (NAION)
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4
Q

causes anorexia

A

quinidine

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5
Q

causes anti-cholinergic/anti-vagal effects

A
  • quinidine- disopyramide
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6
Q

binds acidic drugs (like digoxin or oral anticoagulants)

A

cholestryamine, colestipol, coleselevam

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7
Q

cannot be used with alpha1 blockers or nitrates

A

sildenafil, vardenafil, tadalafil, avanafil, alprostadil

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8
Q

coronary vasodilator

A

adenosine

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9
Q

causes deposits in skin (blue/gray)

A

amiodarone

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10
Q

causes diabetes

A

niacin

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11
Q

enhanced by hypokalemia

A

digoxin

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12
Q

causes fatal pulmonary fibrosis

A

amiodarone

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13
Q

decreases absorption of fat-soluble vitamins

A

cholestryamine, colestipol, coleselevam

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14
Q

first pass effect

A
  • lidocaine- glyceryl trinitrate (nitroglycerin)
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15
Q

causes hemorrhage

A
  • warfarin- dabigatran
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16
Q

causes hypotension

A
  • beta blockers (“olol’s”)- glyceryl trinitrate (nitroglycerin)
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17
Q

causes itching

A

niacin

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18
Q

causes loose stools/leakage

A
  • orlistat- olestra
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19
Q

causes lupus-like syndrome in slow acetylators

A

procainamide

20
Q

metabolized by P450

A
  • sildenafil, vardenafil, tadalafil, avanafil, alprostadil- warfarin- dabigatran- lovastatin, simvastatin, atorvastatin, fluvastatin, pravastatin, rosuvastatin, pitavastatin
21
Q

causes myocardial infarction

A
  • sildenafil, vardenafil, tadalafil, avanafil, alprostadil - epoietin alfa, darbepoietin, peginesatide
22
Q

causes myositis (at worst, rhabdomyolysis)

A

lovastatin, simvastatin, atorvastatin, fluvastatin, pravastatin, rosuvastatin, pitavastatin

23
Q

causes neutropenia

A

ticlopidine

24
Q

causes osteoporosis

A

heparin

25
Q

has an effect on pregnancy

A
  • fondaparinux- warfarin (category X)- hydroxyurea (category D)- lovastatin, simvastatin, atorvastatin, fluvastatin, pravastatin, rosuvastatin, pitavastatin (category X)- folic acid deficiency (neural tube defect)
26
Q

prodrug

A
  • dabigatran- lovastatin, simvastatin, atorvastatin, fluvastatin, pravastatin, rosuvastatin, pitavastatin
27
Q

causes skin flushing

A
  • glyceryl trinitrate (nitroglycerin)- niacin
28
Q

given via injection/subcutaneously

A
  • heparin (too large)- fondaparinux- hirudin- vitamin B12 (for pernicious anemia)
29
Q

given sublingually

A

glyceryl trinitrate (nitroglycerin)

30
Q

given via IV

A
  • lidocaine (first pass)- adenosine- abciximab- tirofiban, eptifibatide- streptokinase, urokinase, tissue plasminogen activator
31
Q

causes spinal hematoma

A

enoxaparin, dalteparin

32
Q

causes thrombocytopenia

A
  • heparin (heparin-induced thrombocytopenia)- abciximab- tirofiban, eptifibatide
33
Q

causes uric acid and gout

A

niacin

34
Q

causes liver damage

A
  • amiodarone- lovastatin, simvastatin, atorvastatin, fluvastatin, pravastatin, rosuvastatin, pitavastatin- lomitapide
35
Q

used for atrial tachycardia

A

adenosine

36
Q

drug of choice for cardiac arrests

A

amiodarone

37
Q

used for digoxin poisoning

A

anti-digoxin antibodies

38
Q

used for heparin overdose

A

protamine sulfate

39
Q

used if patient has heparin-induced thrombocytopenia

A

hirudin

40
Q

used for acute iron overdose

A

chelating agent (deferoxamine)

41
Q

used for chronic iron overdose (hemachromatosis)

A

phlebotomy (bleeding)

42
Q

used for pernicious anemia

A

vitamin B12 injected

43
Q

used for plastic surgery

A

bivalirudin, desirudin, argatroban

44
Q

used for pulmonary hypertension

A

sildenafil, vardenafil, tadalafil, avanafil, alprostadil

45
Q

used post-surgery for spinal tap or spinal surgery

A

rivaroxaban, apixaban

46
Q

used for ventricular tachycardia

A

lidocaine, mexiletine

AU14 - Pharm Exam 3 (1 decks)

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