Atypical Mycobacteria Flashcards
Why are the atypical mycobacteria atypical?
They are environmentally acquired infections that cause neither Tb nor leprosy
How does atypical mycobacterial infection manifest in an immunocompetent adult?
Cutaneous infection
How does atypical mycobacterial infection manifest in kids?
Scrofula
Immunosuppressed hosts can have systemic symptoms from atypical mycobacterial infection- what two bugs are most likely to cause this?
M. kansasii or MAI/MAC
Is it easy to treat atypical mycobacterial infections?
No!
Are antibiotics required to treat atypical mycobacterial infections?
May require multiple antibiotics
Can M. leprae be cultured?
No
What is the slowest growing human pathogen?
M. leprae
What temperature does M. leprae prefer?
30 C
Describe the incubation period of M. leprae
It’s very long
Does M. leprae transmit easily?
No
Are most humans susceptible to disease by M. leprae?
No- only 5-10%
What are the two classifications of Leprosy (Hansen’s Disease)?
Tuberculoid to Lepromatous
Describe tuberculoid leprosy
Strong CMI response contains infection and damages nerves. Few Bacilli are seen. Positive PPD
Describe lepromatous leprosy
Weak CMI response. Many bacilli are seen. Extensive cutaneous symptoms. Negative PPD.