Atypical Bacteria Flashcards
1
Q
Treponema pallidum
A
Keys:
- spirochete
- rabbit testis
- chancre
- RANC
Extras:
- Congenital: saddle nose, mulberry molars, hutchinson teeth, rhinitis, osteochondritis
- organ endarderitis
- Tabes dorsalis - Argyll Robertson pupils
- Benzathine penicillin G
2
Q
Borrelia burgdorferi
A
Key:
- spirochete
- erythema migrans (targetoid)
- tick bite
- northeast/midwest region
Extras:
- boys 5-19
- spirochete
- transient Ops (vf)
- flu-like symptoms
- child blindness
- child arthritis
3
Q
Borrelia afzelli
A
Key:
- spirochete
- old woman
- acrodermatitis chronic atrophicans
- European ticks/fleas
4
Q
Chlamydia (general)
A
- intracellular
- biphasic
- (EB[metabollic spore epithelial invasion] -> RB[intra-c replication -> EB[lysis/extrusion])
- cAMP / cGMP mediated
- LPS
5
Q
Chlamydia trachomatis
A
Ocular:
- increase blindness
- hand eye child transmission
- recurrent cojunctivitis
Genital:
- highly asymptomatic
- male: NGU
- female: cervicitis, ectopic pregnancy
- babies: conjuctivits, pneumonia
6
Q
Chlamydia psittaci
A
- bird sneeze -> human transmission
- atypical pneumonia
7
Q
Chlamydia pneumoniae
A
Key:
- TWAR strain
- pear shape
- ALL ppl acquire
- school age child
Extra:
- bronchitis
- preceding pharyngitis/laryngitis
- asymptomatic spread
- human -> human
8
Q
Ehrlichia chaffeensis
A
- *morulae
- monocyte target
- southeastern region
- tick transmission
- *positive aminotransferase labs
- lypho/thrombocytopenia
9
Q
Anaplasma phagocytophilium
A
- HGE: human granulocytic ehrlichia
- neutrophil morulae
10
Q
Rickettsia rickettsii
A
Key
- intracellular gram (-) bacillus
- adult tick/dog transmission
- southeastern region
- Omp A/B (vf)
- ankle/wrist -> palm/sole petechiae
Extra
- diffuse rash
- G6PD deficiency susceptible
- need > 10 hrs of tick attachment transmission
- CD8 needed clearance
11
Q
Rickettsiae prowazekii
A
- typhus disease
- body louse -> human transmission
- U.S. (flying squirrels), beyond (human->human)
- *rash + pneumonia
- *doxycycline treatment
12
Q
Mycobacterium tuberculosis
A
Key
- acid fast V shaped/parallel bacillus
- (*LAM)/complement/mannose macrophage binding
- Gohn complex
- fever + cachexia
Extra
- slow growth (AB resistance)
- high lipid content cell wall (mycolic acid)
- CD4 mediated–macrophage activation
- primary- located in mid-low lung
- post primary- upper (right) lung
- granulomas
- fever + fatigue + hemoptysis + cachexia
- upper lung cavities
13
Q
Mycoplasma pneumoniae
A
Key
- naked (smallest bacteria) sterol membrane
- H2O2 cilial loss
- atypical bronchial pneumonia
- IgM cold agglutins
Extra
- fried egg culture appearance
- mulberry colonies
- no colonization –> instant or no infection
- bind to epithelial neuraminic acid (no penetration)
- damage (cilial loss)
*
14
Q
Ureaplasma urealyticum
A
- NGU
- asymptomatic
15
Q
A
