Atrial Fibrillation Flashcards

1
Q

What is acute/first detected AF?

A

AF with the onset within 48 hours

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is paroxysmal AF?

A

AF that is self-terminating within 7 days, usually within 48 hours

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What is recurrent AF?

A

AF occurring >2 episodes; Paroxysmal or persistent AF

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is persistent AF?

A

AF that is not self-terminating, lasting more than 7 days

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What is permanent AF?

A

AF that lasts for more than a year

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

How common is AF?

A

1% prevalence in population
18% in >65
Prevalence increases with age

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Who does AF affect?

A

1/3 in patients after coronary bypass surgery and >1/2 undergoing valvular surgery

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What is the aetiology of AF?

A
  • Disorganised, rapid and irregular activation of the atria (300-600 bpm)
  • Irregular ventricular response as an effect
  • Irregularly irregular heartbeat
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What are the causes of AF? (Heart conditions)

A
  • Generally increased intra-cardial pressure
  • atherosclerosis
  • Myocardial Infarction
  • congestive heart failure
  • left ventricular hypertrophy
  • valvular heart disease (mitral regurgitation, aortic stenosis)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What are the causes of AF?

A
  • pulmonary embolism
  • pneumonia
  • hypertension
  • hyperthyroidism
  • post operative (hypokalaemia, hypomagnesia)
  • alcohol, caffeine
  • sarcoidosis
  • obesity
  • idiopathic/ ‘lone’ AF
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What are the risk factors of AF?

A
  • age
  • diabetes
  • obesity
  • HTN
  • smoking, caffeine, alcohol
  • metabolic syndrome
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What are the symptoms of AF?

A
  • asymptomatic (in up to 20% of cases)
  • chest pain
  • palpitation
  • dyspnoea
  • faintness (actual syncope is rare)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What are the signs of AF on examination?

A
  • irregularly irregular pulse
  • 1st heart sound of variable intensity/loudness
  • apical pulse rate is greater than radial pulse rate
  • signs of left ventricular failure (pink frothy sputum, tachypnoea, orthopnoea, rapid pulse)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What are the differential diagnosis of AF?

A
  • Atrial flutter (saw-toothed ECG; may be irregular or regular, usually tachycardic)
  • Supraventricular tachyarrhythmia
  • Wolff-Parkinson-White syndrome
  • Ventricular tachycardia
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What are the investigations to confirm the diagnosis of AF?

A

-ECG
-Bloods:
..TFTs (thyrotoxicosis can precipitate event),
..Us+Es (look for electrolyte disturbances/renal failure- abnormal serum potassium levels can potentiate arrhythmia),
..cardiac enzymes (investigate MI as primary or secondary event)
-Echocardiogram: for left atrial enlargement, mitral valve disease, structural abnormalities

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What would an ECG finding of an AF look like?

A
  • no P wave
  • narrow QRS complex
  • irregular baseline
  • irregularly irregular rhythm
17
Q

What are the treatments of AF when caused by acute precipitating event?

A

Underlying cause should be treated:

  • alcohol toxicity
  • chest infection
  • hyperthyroidism
18
Q

What is the treatment for AF in haemodynamically unstable patients?

A

1) Immediate heparinisation -> administer heparin
2) Attempt cardioversion -> synchronised DC shock
3) If cardioversion fails/AF recur->IV amiodarone
- then attempt another cardioversion

19
Q

What is the treatment for AF in stable patients?

A

Two strategies available:

1) Rate control
2) Rhythm control

20
Q

What is the principle of rate control treatment in AF?

A

-To reduce heart rate at rest and exercise
-However, pts remains in AF
>Beta-blockers: propanolol, atenolol, bisoprolol
>Calcium antagonist: verapamil/diltiazem
>Digoxin used only in sedentary people

21
Q

What is the principle of rhythm control treatment in AF?

A

1) Electrical DC cardioversion + B-blockers to suppress arrhythmias
2) Pharmacological cardioversion: oral Flecainide

22
Q

What is one of the greatest risk for patients with AF?

A

Thromboembolism.

Anticoagulation may be with apixaban, dabigatran, rivaroxaban or a vitamin K antagonist (eg. warfarin).