ATI: Chapter 80 - Cushing's Disease/Syndrome

Question 1

Cushing’s disease (hypercortisolism) and Cushing’s syndrome are caused by an oversecretion of the hormones the ________ produces.

Answer 1

adrenal cortex

Question 2

Cushing’s disease can be the result of a tumor in the pituitary gland resulting in release of the hormone _______. The _____ then stimulates the adrenal cortex to increase the secretion of the glucocorticoid hormone cortisol. It can also be the result of hyperplasia of the adrenal cortex.

Answer 2

ACTH

ACTH

Question 3

Adrenal Cortex Hormones

Answer 3

Mineralocorticoids
Glucocorticoids
Sex Hormones

Question 4

Aldosterone is a _______.

Answer 4

mineralocorticoid

Question 5

Cortisol is a _______.

Answer 5

glucocorticoids

Question 6

Androgens and estrogens are ______.

Answer 6

sex hormones

Question 7

Mineralocorticoids (aldosterone) increases ________, and causes potassium excretion in the kidney.

Answer 7

sodium absorption

Question 8

Glucocorticoids (cortisol) affects glucose, protein, and fat metabolism; the body’s response to stress; and the body’s ______ function.

Answer 8

immune

Question 9

Advise the client to take medications and watch for adverse reactions. Advise the client that the need for medication therapy can be lifelong with ______.

Answer 9

cushing’s disease

Question 10

Advise the client to eat foods high in calcium and vitamin ________ with Cushing’s syndrome.

Answer 10

D

Question 11

With cushing’s syndrome advise the client not to ingest ________ or caffeine. Advise the client to monitor for indications of gastric bleeding, such as coffee-ground emesis or black tarry stool.

Answer 11

alcohol

Question 12

Advise the client to avoid infection by using good hygiene and _______ or individuals who have infections with Cushing’s disease.

Answer 12

avoiding crowds

Question 13

Advise the client that he might need assistance at home due to residual ___________ with Cushing’s disease..

Answer 13

muscle weakness

Question 14

Instruct the client to weight himself ______ and report weight gain with Cushing’s disease.

Answer 14

daily

Question 15

Women between the ages of _____ and _____ years old is a risk factor for Cushing’s disease.

Answer 15

20 to 40 years

Question 16

Endogenous cause of increased cortisol.

Answer 16

adrenal hyperplasia
adrenocortical carcinoma
pituitary carcinoma
pituitary carcinoma that secretes adrenocorticotropic hormone (ACTH)
Carcinomas of the lung, gi, or pancreas (these tumors can secrete ACTH)

Question 17

Exogenous causes of increased cortisol

Answer 17

organ transplant
chemo
autoimmune diseases
asthma
allergies
chronic inflammatory disease

Question 18

Expected findings of cushing’s disease

Answer 18

weakness, fatigue, sleep disturbance
back and joint pain
altered emotional state (irritability, depression)
decreased libido