ATI Flashcards
native immunity aka
nonspecific innate
-restricts entry or immediately responds to a foreign organism (antigen) through the activation of phagocytic cells, complement, and inflammation
passive immunity
Antibodies are produced by an external source
specific adaptive immunity
allows the body to make antibodies in response to a foreign organism (antigen). This reaction directs against an identifiable micro-organism.
chain of infection
agent
reservoir
portal of exit (from the host)
mode of transmission
portal of exit (to the host)
susceptible host
stages of infection
Incubation: interval between the pathogen entering the body and the presentation of the first finding
Prodromal stage: interval from onset of general findings to more distinct findings; during this time, the pathogen multiplies
Illness stage: interval when findings specific to the infection occur
Convalescence: interval when acute findings disappear, total recovery taking days to months
what is HAIs
Health-care associated infections (HAIs) are infections that a client acquires while receiving care in a health care setting
antipyretics
Antipyretics (acetaminophen and aspirin) are used for fever and discomfort as prescribed
antimicrobial therapy
kills or inhibits the growth of micro-organisms (bacteria, fungi, viruses, protozoans). Antimicrobial medications either kill pathogens or prevent their growth. Give anthelmintics for worm infestations.
fire response vs fire extinguisher
-RACE: rescue, alarm, contain/confine, extinguish
-PASS: pull, aim, squeeze, sweep
Virulence
the ability of a pathogen to invade the host and cause disease
what kind of cells causes an inflammatory response?
-Phagocytic cells (neutrophils, eosinophils, macrophages), the complement system, and interferons are involved.
-An inflammatory response localizes the area of microbial invasion and prevents its spread.
specific adaptive immunity
-Allows the body to make antibodies in response to a foreign organism (antigen)
-Requires time to react to antigens
-Provides permanent immunity due to memory of past exposures
-Involves B and T lymphocytes
-Produces specific antibodies against specific antigens (immunoglobulins: IgA, IgD, IgE, IgG, IgM)
what is ESR
-Erythrocyte sedimentation rate (ESR): The rate at which red blood cells settle out of plasma.
-An elevated ESR is an indicator of an active inflammatory process or infection (expected reference range is 15 to 20 mm/hr).
-An increase indicates an active inflammatory process or infection.
what is immunoglobulin electrophoresis
-Determines the presence and quantity of specific immunoglobulins (IgG, IgA, IgM)
-Used to detect hypersensitivity disorders, autoimmune disorders, chronic viral infections, immunodeficiency, multiple myeloma, intrauterine infections