Asthma Monoclonal Medications

Question 1

Nucala (Mepolizumab)

Answer 1

Available: 100mg reconstituted solution
Dose: 100mg SQ every 4 weeks

Question 2

Cinqair (Reslizumab)

Answer 2

Available: 100mg/10mL vial
Dose: 3mg/kg IV every 4 weeks

Question 3

Xolair (Omalizumab)

Answer 3

Available: 150mg reconstituted solution
Dose: dose info based on weight and pre-treatment IgE levels; SQ every 4 weeks

Question 4

Fasenra (Benralizumab)

Answer 4

Available: 30mg/mL
Dose: 30mg SQ every 4 weeks for 3 doses then every 8 weeks

Question 5

Dupixent (Dupilumab)

Answer 5

Available: 300mg/2mL
Dose: MODERATE/SEVERE- 400mg (2 200mg injections) or 600mg (3 injections) SQ; MAINTENANCE- 200mg (following 400mg initial dose) or 300mg (following 600mg initial dose) once every other week

Other indications: OCS dependent or with moderate/severe atopic dermatitis, atopic dermatitis, or rhinosinusitis with nasal polyposis