Asthma Meds Flashcards
Budesonide
Inhaled corticosteroid nebulizer suspension approved for children age 1-8 (SABA)
Fluticasone
Inhaled corticosteroid dry-powder inhalation approved for children age 4 and older
Combined salmeterol/flucitasone
Dry powder inhalation or HFA MDI approved for children 4 and older
Moteleukast (2)
CONTROL
- LTRA 4mg chewable tablet for 2-6 years old
- LTRA 4mg granules approved for 1 and older
Cromolyn nebulizer
CONTROL; Approved for 2 and up
Severity of asthma with stepwise approach (4)
Intermittent: Step 1
Mild persistent: Step 2
Moderate persistent: Step 3 or 4
Severe persistent: Step 5 or 6
Stepwise approach for managing asthma in 0-4 years old (6 steps)
Step 1: SABA PRN
Step 2: Low dose ICS (alt: Cromolyn or Monteleukast)
Step 3: Medium dose ICS
*Consult with asthma specialist
Step 4: Medium dose ICS + either LABA or Monteleukast
Step 5: High dose ICS + either LABA or Monteleukast
Step 6: High dose ICS + either LABA or Monteleukast w/ oral systemic corticosteroids
Stepwise approach for managing asthma in 5-11 years old (6 steps)
Step 1: SABA PRN
Step 2: Low dose ICS (alternative: LTRA, Cromolyn Nedocromil or Theophylline)
Step 3: Either low dose ICS + LABA, LTRA or Theophylline OR Medium dose ICS
Step 4: Medium Dose ICS + LABA (Alt: Medium Dose ICS + either LTRA or Theophylline)
Step 5: High Dose ICS + LABA (Alt: High dose ICS + either LTRA or Theophylline)
Step 6: High dose ICS + LABA + OCS (Alt: High dose ICS + either LTRA or Theophylline + OCS)
Stepwise approach for managing asthma in 12 and older (6 steps)
Step 1: SABA PRN
Step 2: Low dose ICS (alternative: LTRA, Cromolyn Nedocromil or Theophylline)
Step 3: Low dose ICS + LABA -OR- Medium Dose ICS
Step 4: Medium Dose ICS + LABA (Alt: Medium Dose ICS + either LTRA or Theophylline or Zileuton)
Step 5: High Dose ICS + LABA -AND- Consider Omalizumab for patients with allergies
Step 6: High dose ICS + LABA + OCS -AND- Consider Omalizumab for patients with allergies
Assessing Control in 0-4 years old (well, not well, very poorly controlled)
Well Controlled: symptoms = 2 days/week, nighttime awakenings only 1x/month, no interference with normal activity and SABA use only =2 days/week
Not Well Controlled: >2 days per week of symptoms, >1x/week of nighttime awakening, some limitation to normal activity and SABA use >2days/week
Very Poorly Controlled: symptoms throughout the day, nighttime awakening >1x/week, extremely limited activity and SABA several times per day
Assessing Control in 5 and older (well, not well, very poorly controlled)
Well Controlled: symptoms = 2 days/week but not more than once each day, nighttime awakenings = 1x/month, no interference with normal activity, SABA =2 days/week
*FEV= >80%
Not Well Controlled: >2 days per week of symptoms, >/=2x/month of nighttime awakening, some limitation to normal activity and SABA use >2days/week
*FEV=60-80%
Very Poorly Controlled: symptoms throughout the day, nighttime awakening >/=2x/week, extremely limited activity and SABA several times per day
*FEV=<60%
What indicates need to step up treatment? (2)
- At 0-4 years old, no improvement with treatment after 4-6 weeks
- At 12+, needing to use of SABA >2 days a week for symptom relief