Asthma / COPD Medications Flashcards
Medication classes used in asthma
7 medication classes
• Short acting beta2 agonists (SABA)
• Inhaled corticosteroids (ICS)
• Long-acting beta agonists (LABA)
• Long-acting muscarinic antagonist (LAMA) (aka “anticholinergics”)
• Leukotriene modifiers
• Theophylline
• Biologics
SABA
Short acting beta2 agonist
Rescue therapy only
MOA - stimulates beta-2 receptors in the lungs causing relaxation of bronchial smooth muscle resulting in bronchodilation
Side effects – tremor, shakiness, lightheadedness, cough, palpitations, hypokalemia, tachycardia, hyperglycemia, tachyphylaxis (diminished effect with increased use)
Inhalation kinetics –
• Onset bronchodilation: 5-15 minutes
• Duration: 2-6 hours
Albuterol
Levalbuterol
Albuterol
Proair, Proventil, Ventolin
SABA
Levalbuterol
Xopenex
SABA
Salmeterol
Serevent
LABA
Formoterol
Foradil
LABA
In COPD: Brand Perforomist
Available only as Nebulizer solution
Olodaterol
Striverdi
LABA
Indacaterol
Arcapta
LABA
Arformoterol
Brovana
LABA
Nebulizer solution only
Ipratropium
Atrovent
SAMA (only agent!)
Tiotropium
Spiriva
LAMA
Aclidinium
Tudorza
LAMA
Umeclidinium
Incruse
LAMA
Glycopyrrolate
Seebri
LAMA
Revefenacin
Yupelri
LAMA
Nebulizer solution only
Fluticasone Propionate
Flovent
Inhaled Corticosteroid (ICS)
Fluticasone Furoate
Arnuity
ICS
Ciclesonide
Alvesco
ICS
Beclomethasone
Qvar
ICS
Mometasone
Asmanex
ICS
Budesonide
Pulmicort
ICS
Flunisolide
Aerospan
ICS
Albuterol / Ipratropium
Combivent, DuoNeb
SABA / SAMA
Indacaterol / Glycopyrrolate
Utibron
LABA / LAMA
Olodaterol / Tiotropium
Stiolto
LABA / LAMA
Vilanterol / Umeclidinium
Anoro
LABA / LAMA
Glycopyrrolate / Formoterol
Bevespi
LAMA / LABA
Fluticasone furoate / vilanterol
Breo
LABA / ICS
ICS Therapy - Counseling Point!
Rinse and Spit!
Fluticasone propionate / salmeterol
Advair, Wixela, AirDuo
ICS / LABA
Budesonide / Formoterol
Symbicort
ICS / LABA
Mometasone / Formoterol
Dulera
ICS/ LABA
Budesonide/ glycopyrrolate / formoterol
Breztri
ICS / LAMA / LABA
Fluticasone furoate / Umeclidinium / vilanterol
Trelegy
ICS / LAMA / LABA