Asthma + COPD + ENT Flashcards
What is the first line investigation for someone suspected with asthma?
Spirometry with bronchodilator reversibility
Fractional exhaled nitric oxide
If there is diagnostic uncertainty after first line investigations for asthma then what follow up test could be done?
Peak flow diary - measure peak flow several time a day for 2-4 weeks
Direct bronchial challenge test with histamine or methacholine
What additional management should be given to pts with asthma other then the inhalers?
Individual asthma self-management programme
Yearly flu jab
Yearly asthma review
Advise on exercise and stop smoking
What is MART therapy?
Maintenance and reliever therapy - when SABA is stopped and only ICS/LABA (Fostair) is used for both daily preventer and reliever
What inhaler technique is used for aerosol inhalers?
Inhale slow and steady
What inhaler technique is used for DPI?
Inhale quick and deep
What is the aim of asthma treatment?
Control disease with minimal side effects
Control:
- no daytime symptoms
- no night time awakening due to asthma
- no need for rescue medications
- no exacerbations
- no limitations on activity including exercise
- normal lung function
Which conditions are included in atophy?
Asthma
Hay fever
Eczema
Allergic rhinitis
What should children under the age of 5 with asthmatic symptoms be suspected for?
Viral wheeze
Try treatment with SABA inhaler and see if symptoms improve
Monitor closely so see how often the use and if it works. Steroids may be tried for short period of time but if uncertainty then refer to resp paediatrician.
What is the MRC dyspnoea scale?
Used to assess the impact of breathlessness in COPD pts
What are the different grading of the MRC dyspnoea scale?
Grade 1 - breathless on strenuous exercise
Grade 2 - breathless on walking up hill
Grade 3 - breathless that slows walking on the flat
Grade 4 - stop to catch breath after waking 100 m on the flat
Grade 5 - unable to leave the house due to breathlessness
How can the severity of COPD be assessed?
Using the FEV1
Stage 1 - >80% of predicted
Stage 2 - 50-79%
Stage 3 - 30-49%
Stage 4 - <30%
What other investigations other then a spirometry can be done to help diagnosis COPD and exclude other conditions?
Chest x-ray FBC - polycythaemia - raised hb in chronic hypoxia BMI - baseline weight to assess any weight change in the future Sputum culture ECG/ECHO CT thorax Serum alpha-1 antitrypsin TLCO - decreased in COPD
What is the most important intervention in COPD?
Smoking cessation
What should patients with COPD be offered alongside inhalers?
Pts with MRC score > 2 pulmonary rehab
Lifestyle advise + exercise
Vaccinations - flu/pneumococcal
Smoking cessation
What is an exacerbation of COPD defined as?
Change in sputum colour
Increased quantity of sputum
Increased breathlessness
What are additional options available in more severe cases of COPD?
Nebulisers (salbutamol and/or ipratopium)
Oral theophylline
Oral mucolytic therapy to break down sputum (e.g. carbocisteine)
Long term prophylaxis antibiotics - specialist only
Longe term oxygen therapy at home
When is LOT indicated in COPD?
Chronic hypoxia <92%
Polycythaemia
Cyanosis
Heart failure - cor pulmonale
When can LOT not be used in COPD?
If the pt smokes and this is a fire hazard
What is the medical treatment for an exacerbation of COPD if the pt is well enough to stay at home?
Prednisolone 30 mg OD for 7-14 days
Regular inhalers or home nebulisers
Antibiotics if there is evidence of infection
What is the initial management for acute bronchitis?
Smoking cessation
Adequate analgesia
Fluid intake
When are antibiotics indicated in acute bronchitis?
Systemically unwell
High risk of complications
Immunocompromised
What is the first line antibiotic for acute bronchitis in over 18 yrs?
Oral doxycycline: 200 mg on first day the 100 mg for 4 days - don’t give in pregnant women
What are alternative choices of antibiotics for acute bronchitis?
Amoxicillin - 500mg three times a day for 5 days - preferred in pregnant women - first line in 12-17 yr olds
Clarithromycin - 250mg to 500mg twice a day for 5 days
Erythromycin - 250-500mg 4 times a day for 5 days or 500-1000mg 2 times a day for 5 days (preferred in pregnant women)
What tool is used to assess severity of community acquired pneumonia?
CRB-65 / CURB-65
What is the CRB-65 tool?
Confusion
Resp rate >/= 30
Bp systolic < 90 or diastolic <60
65 yrs old
What is the antibiotics of choice if the CRB-65 score is 0 and no hospital assessment is required?
Amoxicillin 500mg 3 times a day for 5 days
If allergic to penicillin then doxycycline or clarithromycin/erythromycin
What safety netting should be given to someone started on antibiotics for pneumonia?
See medical advise if:
- symptoms worsen rapidly or significantly
- symptoms do not start to improve in 3 days or as expected
- become systemically unwell
What is the virus that causes the common cold?
Rhinovirus
What are the complications of the common cold?
LRTI
Sinusitis
Acute otitis media
What is important to assess in suspected allergic rhinitis?
Atophy/ family history
Type, freq and location, severity, housing conditions, pets, occupation
What is the management of allergic rhinitis?
Info about disease
Nasal irrigation with saline
Avoid trigger if identified
Mild to moderate - internasal antihistamine prn
Moderate to severe - internasal corticosteroids
Review in 2-4 weeks if don’t improve
What is the treatment for bacterial tonsillitis?
Penicillin V - 10 days
If allergic the clarithromycin/erythromycin
Arrange urgent bloods in immunodeficiency patient
What are the differential diagnosis for tonsillitis?
Common cold
Glandular fever
Epiglottis