Asthma & COPD Flashcards
What is a wheeze?
A continuous, coarse, whistling sound produced in the respiratory airways during breathing
Formally called “sibilant rhonchi” in medical terminology
What can cause wheezing?
Narrowing or obstruction of the respiratory tree or heightened airflow velocity
Includes conditions like asthma and COPD
What is asthma?
A heterogeneous disease characterized by chronic airway inflammation, respiratory symptoms that vary over time, and variable expiratory airflow limitation
Symptoms include wheeze, shortness of breath, chest tightness, and cough
What are the 3 cardinal features of asthma?
- Variability
- Precipitants
- Reversibility
How many individuals are estimated to be affected by asthma worldwide?
Approximately 300 million
What are some risk factors for asthma?
- Genetic characteristics
- Occupational exposures
- Environmental exposures
What is COPD?
A common preventable and treatable disease characterized by persistent airflow limitation that is usually progressive and associated with chronic inflammatory responses
Exacerbations and comorbidities contribute to severity
What are the goals of asthma therapy?
- Symptom control
- Risk reduction
What are the primary treatment options for asthma?
- Inhaled corticosteroids (ICS)
- Short acting beta-2 agonists (SABA)
- Long acting beta-2 agonists (LABA)
- Combination therapies
What are the recommended approaches for COPD therapy?
- Smoking cessation
- Pulmonary rehabilitation
- Vaccination
- Treat comorbidities
What is the significance of differentiating between asthma and COPD?
Affects patient expectations, response to therapy, and long-term prognosis
What are the typical spirometric tracings used to diagnose asthma?
FEV1 measurements before and after bronchodilator (BD) administration
What does GOLD stand for in the context of COPD?
Global Initiative for Chronic Obstructive Lung Disease
Fill in the blank: Asthma is characterized by _______.
chronic airway inflammation
True or False: COPD symptoms begin after age 40 years.
True
What are the common symptoms of asthma?
- Wheezing
- Shortness of breath
- Chest tightness
- Cough
What defines a persistent wheeze?
A wheeze that occurs consistently over time
What is the primary treatment option for COPD?
Bronchodilators
What does the mMRC scale assess in COPD patients?
The degree of breathlessness
What is the role of inhaled steroids in asthma treatment?
They are the primary treatment option for controlling asthma symptoms
What is the importance of smoking cessation in COPD management?
Reduces the rate of decline in FEV1 and the risk of pneumonia, cancer, and cardiovascular diseases
What is a key characteristic of COPD symptoms?
Continuous respiratory symptoms with little day-to-day variation
How does asthma differ from COPD in terms of symptom variability?
Asthma exhibits variable airflow limitation and day-to-day variation in symptoms
What are biological therapies in asthma management?
Infusion or subcutaneous treatments targeting IgE and interleukins