Asthma and COPD Flashcards
define obstructive respiratory disease
conditions that cause the narrowing of the large, medium and small sized airways (bronchi)-> this results in air trapping and hyperinflation.
spirometry in obstructive respiratory disease
low fev1 and normal fvc and therefore, fev1/fvc <70%
asthma is characterised by
rrecurrent attacks of breathlessness and wheezing, varies in severity and frequency from person to person.
more than one of wheeze, breathlessness, chest tightness, cough
epidemiology of asthma
2.6-4/1000 individuals in the uk (3-34% worldwide)
prevalence is 8% of adults and 20% of children: 5.4M people in the uk
1500 deaths every year and 185 hospital admissions every day.
1B spent by the nhs in treating asthma
deaths in the uk is 50% greater than in the EU
aetiology of asthma
airways inflammation (type I hypersensitivity)that occurs when a genetically susceptible inidividual with atopy is exposed to certain environmental factors