Asthma Flashcards
asthma
- chronic INFLAMMATORY disorder of airways 2. intermittent OBSTRUCTION 3. airway HYPER-ACTIVITY
is obstruction in asthma reversible?
often yes
asthma risk factors
hx of atopic dz, FH of asthma/allergy, tobacco exposure, GERD, vocal cord dysfunction, RSV, maternal smoking
symptoms of asthma
dyspnea, cough, wheezing, chest tightness
cough in asthma is worse
night
asthma worsen by
exercise, URI, allegens, emotion, irritants
ACE inhibitors cause
chronic dry cough
PE findings of asthma
expiratory wheezing, prolonged expiratory phase, tachypnea, tachycardia , pulsus paradoxus , accessory muscle use, atopic dz
asthma initial dx
detailed medical hx, PE, PFT (>5years of age), methacholine challenge test (not done currently)
PFT confirmed dx of asthma
> 12% improvement in FEV1 with bronchodilator
obstructive graph in spriometry
concave
peak expiratory flow meter
red, yellow, green zone
when to use PEFM
in conjunction w.written tx plans for pt compliance on regular basis and during exacerbation
intermittent asthma
all ages: sx 80%
mild asthma
sx>2x/wk (not daily)
age 0-4: >2nits/mt
age >5: 3-4nits/mt
minor limitation, FEV1>80%
moderate persistent asthma
daily sx,
age 0-4: 3-4 nit/mt
age >5:sx >1nite/wk
exacerbation >2/wk, affect activity, last days, FEV1 60-80%
sever persistent asthma
continuous sx,
age 0-4: >1x/wk nite sx
age >5: oftern 7x/wk nite sx
limited physical activity, frequent exacerbations, FEV1<60%
tx asthma
beta 2 agonists, corticosteroids, mast cell stabilizers, leukotriene modifiers (LTRA), anticholinergics, methylxanthines, immunomodulators
tx intermittent asthma
SABA PRN
tx mild persistent asthma
low dose ICS + SABA
cromolyn
tx of mild persistent asthma (0-4 yr)
Leukotriene receptor antagonist/cromolyn
tx of mild persistent asthma (5-11 yr)
tx of moderate persistent asthma
refer to specialist
0-4: medium dose ICS
5-11: medium dose ICS /low dose ICS+LTRA/ long acting beta 2 agonist
tx of sever persistent asthma
0-4: medium dose ICS + LABA/LTRA
5-11: medium dose ICS +LABA
when to add oral steroids to High dose ICS + LABA
severe severe cases -step 6
tx intermittent asthma adults
SABA (albuterol) as rescue PRN
tx of mild asthma adult
low dose ICS / leukotriene inhibitor, nedocromil, theophylline
tx of moderate persistent asthma adult
low dose ICS + LABA (advair) /medium dose ICS
xolair
pt with allergies and step 5 asthma
oral CS
asthma adult step 6 -added to high dose ICS+ LABA
important vital sign for asthma
RR -tachypnea
cbc for asthma
r/o infection
peak expiratory flow
mild >70%-out pt
moderate 40-70%- ED
Severe < 25% -ICU
common finding of asthma on ABG
respiratory alkalosis due to hyperventilation
EKG monitoring for asthma
watch for hypokalemia -prolonged QT interval
IV steroid for asthma
initially if PEF <50%
abx for asthma
only if infection/pneumonia
tx to exhale more CO2 for asthma if needed
C-PAP, BiPAP, intubation
first line tx of asthma
ICS