Associations Flashcards
LDH
dysgerminoma
seminoma
PTEN
endometrial carcinoma (endometrioid type)
p53
endometrial carcinoma (serous type)
ovarian cancer (high grade serous)
i(12p)
testicular cancer
TMPRSS2/ERG fusion
prostate cancer
LSIL vs HSIL
nuclear:cytoplasmic ratio
HSIL: nucleus takes up almost entire cell (higher ratio)
LSIL: more cytoplasm
neither form a mass
fused glands
adenocarcinoma
epithelial cell ovarian tumors are more common in ______
ADULTS (pre/peri/post menopausal)
serous mucinous endometrioid clear cell Brenner
germ cell ovarian tumors are more common in ______
young adults (15-20 ish yrs)
dysgerminoma embryonal yolk sac choriocarcinoma teratoma
sex cord stromal ovarian tumors are more common in ______
older adults (50’s)
granulosa
thecoma/fibroma
sertoli-leydig exception (24 yrs)
solid ovarian tumors
dysgerminoma choriocarcinoma immature teratoma thecoma/fibroma sertoli/leydig
call-exner body
granulosa tumor (ovarian) ESTROGEN
coffee bean nucleus
granulosa tumor (ovarian)
HCG
choriocarcinoma
AFP
yolk sac
CA 125
serous adenocarcinoma
serotonin
carcinoid
thyroid hormone
struma ovarii
estrogen
theca/granulosa
androgen
leydig
causes of endometrial CA
granulosa/thecoma (unopposed estrogen)
endometrioid CA of ovary
fallopian tube STIC
serous carcinoma of ovary
psammoma bodies
serous carcinoma of ovary (any papillary tumor)
AFP
yolk sac
acetylcholinesterase
neural tube defect
proliferative breast lesions with an increased risk of carcinoma:
adenosis
intraductal papilloma
papilloma
lined by epithelium
stromal core
intraductal papilloma
- epithelial lining w no atypia
- fibrous stroma
- slit like space
- well demarcated
fibroadenoma
hyperplastic nodules of stroma/glands lined by 2 layers of epithelium
BPH
glands lined by a single layer of epithelium and packed back to back
adenocarcinoma
foci of chronic inflammatory cells in the stroma and normal appearing glands
prostatitis
areas of necrosis filled w neutrophils
abscess
