Associations Flashcards

1
Q

LDH

A

dysgerminoma

seminoma

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2
Q

PTEN

A

endometrial carcinoma (endometrioid type)

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3
Q

p53

A

endometrial carcinoma (serous type)

ovarian cancer (high grade serous)

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4
Q

i(12p)

A

testicular cancer

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5
Q

TMPRSS2/ERG fusion

A

prostate cancer

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6
Q

LSIL vs HSIL

A

nuclear:cytoplasmic ratio

HSIL: nucleus takes up almost entire cell (higher ratio)

LSIL: more cytoplasm

neither form a mass

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7
Q

fused glands

A

adenocarcinoma

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8
Q

epithelial cell ovarian tumors are more common in ______

A

ADULTS (pre/peri/post menopausal)

serous
mucinous
endometrioid
clear cell
Brenner
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9
Q

germ cell ovarian tumors are more common in ______

A

young adults (15-20 ish yrs)

dysgerminoma 
embryonal 
yolk sac
choriocarcinoma
teratoma
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10
Q

sex cord stromal ovarian tumors are more common in ______

A

older adults (50’s)
granulosa
thecoma/fibroma

sertoli-leydig exception (24 yrs)

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11
Q

solid ovarian tumors

A
dysgerminoma
choriocarcinoma
immature teratoma
thecoma/fibroma
sertoli/leydig
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12
Q

call-exner body

A
granulosa tumor (ovarian)
ESTROGEN
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13
Q

coffee bean nucleus

A

granulosa tumor (ovarian)

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14
Q

HCG

A

choriocarcinoma

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15
Q

AFP

A

yolk sac

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16
Q

CA 125

A

serous adenocarcinoma

17
Q

serotonin

A

carcinoid

18
Q

thyroid hormone

A

struma ovarii

19
Q

estrogen

A

theca/granulosa

20
Q

androgen

A

leydig

21
Q

causes of endometrial CA

A

granulosa/thecoma (unopposed estrogen)

endometrioid CA of ovary

22
Q

fallopian tube STIC

A

serous carcinoma of ovary

23
Q

psammoma bodies

A

serous carcinoma of ovary (any papillary tumor)

24
Q

AFP

A

yolk sac

25
Q

acetylcholinesterase

A

neural tube defect

26
Q

proliferative breast lesions with an increased risk of carcinoma:

A

adenosis

intraductal papilloma

27
Q

papilloma
lined by epithelium
stromal core

A

intraductal papilloma

28
Q
  • epithelial lining w no atypia
  • fibrous stroma
  • slit like space
  • well demarcated
A

fibroadenoma

29
Q

hyperplastic nodules of stroma/glands lined by 2 layers of epithelium

A

BPH

30
Q

glands lined by a single layer of epithelium and packed back to back

A

adenocarcinoma

31
Q

foci of chronic inflammatory cells in the stroma and normal appearing glands

A

prostatitis

32
Q

areas of necrosis filled w neutrophils

A

abscess