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Paraneoplastic syndromes > Associated cancers > Flashcards

Associated cancers Flashcards

1
Q

What cancers are Cushings Syndrome associated with?

A
  1. Small cell carcinoma
  2. Pancreatic cancer
  3. Neural tumors
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2
Q

What cancers are Inappropriate secretion of ADH associated with?

A
  1. Small Cell carcinoma of the Lung

2. Intracranial neoplasms

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3
Q

Causal mechanism of Cushing’s Syndrome?

A

Secretion of ACTH or ACTH-like substance

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4
Q

Causal mechanism of IADH?

A

Secretion of ADH or atrial natriuretic hormones

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5
Q

What cancers are hypoglycemia associated with?

A
  1. Ovarian carcinoma
  2. Fibrosarcoma
  3. Mesenchymal tumors (SFT)
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6
Q

Causal mechanism for hypoglycemia?

A

Secretion of insulin or insulin-like substance

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7
Q

What cancers are associated with hypercalcemia?

A
  1. Squamous cell carcinoma of the Lung
  2. Breast carcinoma
  3. Renal carcinoma
  4. Adult T cell leukemia/lymphoma
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8
Q

Causal mechanism of hypercalcemia?

A

PTH-rp, TGF-alpha, TNF, IL-1

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9
Q

What cancers are Myasthenia and disorders of the CNS and PNS associated with?

A
  1. Breast carcinoma

2. Bronchogenic carcinoma

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10
Q

Causal mechanism for Myasthenia?

A

immunologic

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11
Q

What cancers are associated with acanthosis nigricans?

A
  1. Gastric carcinoma
  2. Lung carcinoma
  3. Uterine carcinoma
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12
Q

What cancers are associated with Carcinoid syndrome?

A
  1. HCC
  2. Bronchial adenoma (carcinoid)
  3. Pancreatic carcinoma
  4. Gastric carcinoma
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13
Q

What cancers are associated with polycythemia?

A
  1. Renal carcinoma
  2. Cerebellar hemangioma
  3. HCC
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14
Q

Causal mechanism of Carcinoid Syndrome?

A

Secretion of Serotonin, Bradykinin

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15
Q

Causal mechanism of polycythemia?

A

Secretion of erythropoietin

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16
Q

What cancers are associated with Dermatomyositis?

A
  1. Bronchogenic carcinoma

2. Breast carcinoma

17
Q

What cancer is associated with hypertrophic osteoarthropathy and clubbing of the fingers?

A

Bronchogenic carcinoma

18
Q

What cancers are associated with venous thrombosis (Trousseau phenomenon)?

A
  1. Pancreatic
  2. Bronchogenic
  3. others….
19
Q

Causal mechanism of Trousseau’s phenomenon?

A

Tumor products, such as mucins that activate clotting

20
Q

Red cell aplasia

A

Thymic neoplasms

21
Q

Causal mechanism for nephrotic syndrome caused by various cancers?

A

tumor antigens and immune complexes

22
Q

Causal mechanism for non-bacterial thrombotic endocarditis caused by various cancers?

A

Hypercoagulability

Paraneoplastic syndromes (1 decks)

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