Assessment Flashcards
Branch chain amino acids
leucine, isoleucine, and valine
Aromatic Amino acids
Phenylalanine, tyrosine, tryptophan,
Conditionally essential amino acids
Proline and Arginine. Cysteine, glutamine, glycine, tyrosine
Synthesized primarily in the order intestine And dependent on intestinal metabolism.
Essential amino acids
Methionine Valine Phenylalanine Isoleucine Threonine Tryptophan Histidine Leucine Lysine
histidine, isoleucine, leucine, lysine, methionine, phenylalanine, threonine, tryptophan, and valine.
Essential fatty acid deficiency
Diffuse scaly dermatitis, hair loss, anemia, and thrombocytopenia ( low platelets) hepatomegaly, fatty liver and anemia.
2-4% of total calories as fat should prevent
Lactated Ringer
130 mEq/L 109 chloride 4 mEq/L potassium 28 mEq/L lactate 2.7 mEq/L calcium
Most closely resembles jejunal and ileal electrolyte content (intestines have 10 to 30 mEq/l of bicarbonate as well)
0.9 NS
154 mEq/l sodium and chloride or 9 grams of salt or 3510 mg if sodium.
1 g salt (sodium chloride) = 390 mg sodium. 1 tsp salt = 6 g salt ≈ 2,400 mg sodium = 104 mmol sodium = 104 mEq sodium.May 12, 2016
Vitamin A supplementation for deficiency
25,000 IU/ day for max of 10 days
** caution in liver or renal failure and elderly
Thiamine deficiency
Wernicke’s encephalopathy
Thiamine plays a role in glucose metabolism
Thiamin deficiency
Lactitic acidosis
Thiamine used to convert pyruvate to acetyl CoA
Without thiamine pyruvate is converted to lactic acid
Positive acute phase protein
Increases during inflammation
C- reactive protein
Negative acute phase proteins
Decrease during inflammation
Albumin
Transferrin
Prealbumun
SIADH
Hyponatremia associated with SIADH
Water conserved
Urine concentrated
CNS disease
Malignancy
Lung disease
Urine sodium and osmolality elevated
Hypophosphatemia
Refeeding
DKA
Chronic alcoholism
Increased risk of metastatic calcification of calcium occurs when the ca & and p product is
Exceeds 55
Hyperphosphatemia can decrease
Calcium
Zinc deficiency caused by poor protein intake can cause
Diarrhea
Copper toxicity can cause
Nausea
Vomiting
Diarrhea
And
Wilson’s disease which is coma, hepatic necrosis, liver/renal failure
Copper is excreted in
Bile (80%)
So monitor copper in patients with liver disease
Zinc deficiency is common in
Liver disease so supplementation can improve amino acid metabolism and decrease encephalopathy
Aluminum toxicity can be treated with
Deferoxamine
Factors that can decrease indirect calorimetry
Chest tubes
Nasal oxygen
Dialysis because of loss of CO2 in dialysis coil
Respiratory quotient
0.7 fat oxidation
<0.82 underfeeding or protein oxidation
0.85 to 0.95mixed substrate
> 1 carbohydrate oxidation and overfeeding and potential lipogenesis
Mufflin-St. Joer
Best to estimate needs of obese and non obese
Cheilosis (cracking of corners of the mouth) is associated with deficiency of
Niacin
Riboflavin
Iron
Pyridoxine (B6)
Arginine could be beneficial for patients with
Trauma Surgery Compromised immunity *as it increases production of nitric oxide *increases blood flow
** avoid in those with septic shock **
Colon length
150 cm
Small bowel length
600 cm or 10 feet
Primary fuel of colonocytes
Short chain fatty acids
SCFA are
Acetate
Butyrate
Propionate
SCFA stimulate absorption of
Water and sodium absorption
Fat from oral intake is absorbed
In the duodenum and proximal jejunum
Valproic acid can induce a deficiency of
Carnitine
Involved in metabolism of fatty acids
Idiopathic encephalopathy can be associated with carnitine deficiency
Thiamin deficiency
Edema
Lower extremity weakness
Hair loss could be attributed to
Inadequate protein
B12
Folate
Brittle hair could be due to
Biotin deficiency
Hair color changes could be due to
Zinc deficiency
Dry hair could be due to what deficiency
Vitamin A and E