Aspirin Flashcards
1
Q
Mechanism of action for aspirin?
A
Inhibits cyclo-oxygenase which is necessary to produce thromboxane A2 (a platelet agonist released from granules upon activation)
1
Q
What type of drug is aspirin?
A
An anti-platelet agent
2
Q
Adverse effects of aspirin?
A
Bleeding
- Anti-platelet drugs tend to affect platelet function for their 7-10 day lifespan.
- Stop anti-platelet agents 7 days prior to elective operations.
- If serious bleeding - can reverse with platelet transfusion.
Blocks production of prostaglandins - GI ulceration, bronchospasm.
3
Q
Administration of aspirin?
A
PO (orally)
