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ARVs Flashcards

1
Q

NRTIs

A 
emtricitabine (FTC)
lamivudine (3TC)
zidovudine (ZDV)
tenofovir DF (TDF)
tenofovir alafenamide (TAF)
abacavir (ABC)
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2
Q

emtricitabine: abrv., class, instructions/contraindications

A

FTC

NRTI

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3
Q

lamivudine: abrv., class, instructions/contraindications

A

3TC

NRTI

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4
Q

zidovudine: abrv., class, instructions/contraindications

A

(ZDV)

NRTI

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5
Q

tenofovir DF: abrv., class, instructions/contraindications

A

(TDF)

NRTI

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6
Q

tenofovir alafenamide: abrv., class, instructions/contraindications

A

(TAF)

NRTI

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7
Q

abacavir: abrv., class, instructions/contraindications

A

(ABC)
NRTI
*only in HLA-B5701 negative (due to hypersensitivity reaction)

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8
Q

ABC: drug, class

A

abacavir

NRTI

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9
Q

TAF: drug, class

A

tenofovir alafenamide

NRTI

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10
Q

TDF: drug, class

A

tenofovir DF

NRTI

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11
Q

3TC: drug, class

A

lamivudine

NRTI

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12
Q

FTC: drug, class

A

emtricitabine

NRTI

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13
Q

ZDV: drug, class

A

zidovudine

NRTI

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14
Q

NNRTIs

A 
rilpivirine (RPV)
etravirine (ETR)
doravirine (DOR)
efavirenz (EFV)
nevirapine (NVP)
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15
Q

rilpivirine: abrv., class, instructions/contraindications

A

(RPV)
NNRTI
*Take with food
*Impaired absorption if taking antacids (not rx)

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16
Q

etravirine: abrv., class, instructions/contraindications

A

(ETR)
NNRTI
*Take with food

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17
Q

doravirine: abrv., class, instructions/contraindications

A

(DOR)

NNRTI

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18
Q

efavirenz: abrv., class, instructions/contraindications

A

(EFV)
NNRTI
*Take without food or w/low-fat snack
*QHS to minimize dizziness, drowsiness, decreased concentration

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19
Q

nevirapine: abrv., class, instructions/contraindications

A

(NVP)

NNRTI

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20
Q

NVP: drug, class

A

nevirapine

NNRTI

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21
Q

EFV: drug, class

A

efavirenz

NNRTI

22
Q

DOR: drug, class

A

doravirine

NNRTI

23
Q

RPV: drug, class

A

rilpivirine

NNRTI

24
Q

ETR: drug, class

A

etravirine

NNRTI

25
Q

Protease inhibitors (PIs)

A 
atazanavir (ATV)
darunavir (DRV)
fosamprenavir (FPV)
nelfinavir (NFV)
lopinavir (LPV) + ritonavir (RTV) (BA)
26
Q

atazanavir: abrv., class, instructions/contraindications

A 
(ATV)
PI
*Take with food
*Take w/COBI
*Impaired absorption if taking antacids (not rx)
27
Q

darunavir: abrv., class, instructions/contraindications

A 
(DRV)
PI
*Take with food
*Dosing may depend on resistance
*Take w/COBI or RTV
28
Q

fosamprenavir: abrv., class, instructions/contraindications

A

(FPV)
PI
*No longer used/recommended

29
Q

nelfinavir: abrv., class, instructions/contraindications

A

(NFV)
PI
*No longer used/recommended

30
Q

DRV: drug, class

A

darunavir

PI

31
Q

ATV: drug, class

A

atazanavir

PI

32
Q

lopinavir + ritonavir: abrv., class, instructions/contraindications

A

Kaletra
(LPV)/(RTV)
PI + BA

33
Q

Kaletra: abrv., class, instructions/contraindications

A

(LPV)/(RTV)
lopinavir + ritonavir
PI + BA

34
Q

Entry inhibitors

A

enfuviritide (T-20) = fusion inhibitor
maraviroc (MVC) = CCR5 antagonist
ibalizumab (IBA) = post-attachment inhibotr

35
Q

enfuviritide: abrv., class, instructions/contraindications

A

(T-20)
fusion inhibitor
EI
*No longer used/recommended

36
Q

maraviroc: abrv., class, instructions/contraindications

A

(MVC)
CCR5 antagonist
EI

37
Q

ibalizumab: abrv., class, instructions/contraindications

A

(IBA)
post-attachment inhibitor
EI

38
Q

IBA: drug, class

A

ibalizumab
post-attachment inhibitor
EI

39
Q

MVC: drug, class

A

maraviroc
CCR5 antagonist
EI

40
Q

T-20: drug, class

A

enfuviritide
fusion inhibitor
EI

41
Q

Integrase inhibitors

A

raltegravir (RAL)
dolutegravir (DTG)
bictegravir (BIC)
elvitegravir (EVG)

42
Q

raltegravir: abrv., class, instructions/contraindications

A

(RAL)
II
*separate from meds w/cations (Mg, Fe, Al, Ca)

43
Q

dolutegravir: abrv., class, instructions/contraindications

A

(DTG)
II
*separate from meds w/cations (Mg, Fe, Al, Ca)

44
Q

bictegravir: abrv., class, instructions/contraindications

A

(BIC)
II
*separate from meds w/cations (Mg, Fe, Al, Ca)

45
Q

elvitegravir: abrv., class, instructions/contraindications

A

(EVG)
II
*separate from meds w/cations (Mg, Fe, Al, Ca)

46
Q

EVG: drug, class

A

elvitegravir

II

47
Q

BIC: drug, class

A

bictegravir

II

48
Q

DTG: drug, class

A

dolutegravir

II

49
Q

RAL: drug, class

A

raltegravir

II

50
Q

Boosting Agents

A

ritonavir (RTV) aka “Norvir”

cobicistat (COBI)

51
Q

ritonavir

A

(RTV) aka “Norvir”
BA
*Take with food

52
Q

cobicistat

A

(COBI)
BA
*Take with food

ARVs (2 decks)

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