arterial regulation Flashcards

1
Q

on a basic level, arterial pressure is regulated by __________ and _________

A

cardiac output and total peripheral resistance

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2
Q

baroreceptors are ______ that are located in the walls of carotid sinus and aortic ____ and transduce pressure to nervous __________ that are transmitted to the CNS

A

mechanoreceptors
arch
action potentials

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3
Q

baroreceptors are sensitive to the rate of pressure ______ and changes in ______

A

change

pressure

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4
Q

nerve impulses from baroreceptor stimulation are carried via cranial ____ and ____ to the medulla and ____

A

IX and X

medulla and pons

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5
Q

chemoreceptors in the _____ react to 02, c02, and ____ in blood and _____ to modify autonomic outflow

A

CNS
pH
CSF

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6
Q

the slower component of blood pressure control regulates ______________, which affects arterial pressure (hours to days)

A

blood volume

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7
Q

the faster component (not as fast as autonomics) is mediated through _______ induced vasoconstriction

A

hormone

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8
Q

decrease in arterial pressure causes a decrease in ______________ in the kidneys. Mechanoreceptors in ________ arterioles of kidney sense the decrease in arterial pressure, and __________ cells convert _______ to rennin

A

renal profusion
afferent
juxtaglomerular
prorennin

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9
Q

angiotensin I is converted to angiotensin II by _____ primarily in the ______ and the kidney

A

ACE

lungs

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10
Q

angiotensin II acts on the ________ to stimulate the release of ________

A

adrenal cortex

aldosterone

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11
Q

aldosterone acts on distal renal tubule cells to promote _______ absorption of ______, increasing blood volume

A

increased absorption of NA

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12
Q

angiotensin II also acts as a direct ___________, increasing blood pressure and ______

A

vasoconstrictor

TPR

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13
Q

angiotensin II preferentailly constricts _______ arterioles

A

efferent

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14
Q

angiotensin II stimulates Na - ____ exchange in renal proximal tubule, increasing Na/HC03 reabsoroption

A

H+

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15
Q

volume overload is an example of maladaptive responses of the _________

A

RAAS

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16
Q

in volume overload: in systolic heart failure with low cardiac output, the kidneys sense decreased blood flow, which activates the _______. This causes an ____ in BP and increased _____, which aggravates the heart failure

A

RAAS
increase
total peripheral resistance

17
Q

in cirrhosis of the liver with low serum albumin, inappropriate ________ secretion contributes to the development of _______

A

aldosterone

ascites

18
Q

ADH is secreted from the ________ and promotes renal water reabsorption _____ receptors

A

pituitary

V1

19
Q

secretion of ________ results in stimulation of ______ receptors in arterial smooth muscle, which cause vasoconstriction of arterioles

A

ADH

V2

20
Q

ANP _____ renal Na RE-absorption. Also mediates vasodilation of afferent renal arterioles, ______ of efferent arterioles, which ______ GF

A

inhibit

constriction, which increases glomerular filtration

21
Q

baroreceptor stimulation to increase BP will constrict arterioles and veins, increase _________ of the heart, and increase _______

A

contractility

SA node

22
Q

orthostatic hypotension may indicate ______ volume and autonomic function

A

blood

23
Q

too much hydrogen will cause an increase in _________ _________

A

minute ventilation

24
Q

an aldosterone secreting adrenal tumor may cause ________ and hypertension

A

hypokalemia

25
Q

vasopressin will cause ______ which will cause in increase in _____, and also an increase in renal fluid _________ and therefore increased ________

A

vasoconstriction
arterial pressure
reabsorption
blood volume

26
Q

SIADH (syndrome of inappropriate ADH release) will cause an abnormality in which electrolyte?

A

Na will be very low (so much water dilutes normal amount of Na)

27
Q

ADH is inhibited by ______, atropine

A

alcohol

28
Q

ANP inhibits ________ reabsorption and _______secretion to decrease blood volume and BP

A

sodium

aldosterone