Arterial Aneurysms Flashcards
What is an aneurysm?
A focal permanent dilatation of an artery that is > 1,5 times the normal diameter of the artery
What is ectasia?
Focal dilatation of an artery that is <1,5 the normal diameter but >1 x the diameter
What is arteriomegaly?
Diffuse dilatation of the entire arterial segment
What is aneurysmosis?
Multiple arterial aneurysms with intervening normal arterial segments
5 complications of arterial aneurysms
Rupture Acute or chronic thrombotic occlusion Acute or recurrent thromboembolism Pressure related complications Spontaneous fistulisation
what is a true aneurysm
The wall of the aneurysm (sac) incorporates all the conventional layers of an artery, i.e. the intima, media and adventitia.
what is a false aneurysm?
The wall of the aneurysm comprises adventitia and compressed surrounding tissue only.
what is the aetiology of arterial aneurysms
- degenerative aneurysms
- infective aneurysms
- connective tissue disorders
- trauma
how are arterial aneurysms classified?
Anatomical location · Aneurysm type: True or false (pseudoaneurysms) · Morphology · Size · Aetiology · Clinical presentation
explain the classification of arterial aneurysms based on anatomical location
aortic - abdominal aortic aneurysm, thoraco abdominal aortic aneurysm
non aortic - peripheral, renal,carotid, subclavian
explain the classification of arterial aneurysms based on morphology
fusiform - spindle shaped
saccular - saccular outpouching in an arterial segment ( complicated at a smaller diameter compared to fusiform )
explain the classification of arterial aneurysms based on size and the consequence for treatment
small: asymptomatic, low risk of complications - observe over time
large: even if asymptomatic have a high risk of complication therefore treat early
explain the classification of arterial aneurysms based on aetiology
degenerative: atherosclerotic, fibromuscular dysplasia, intimo medial mucoid degeneration
infective: tb, syphyllis
inflammatory/vascultis: takayasus, giant cell arteritis
connective tissue: marfans, ehler danlos
post dissection: cystic media necrosis, trauma
post stenotic: thoracic outlet syndrome, coarctation of the aorta
trauma:
congenital: turners, menkes syndrome, tuberous sclerosis
what is the most common aneurysm
abdominal aortic aneurysm AAA
how are AAAs classified anatomically?
- Infra-renal: ~ 90% of AAAs are infra-renal
· Juxta-renal: the proximal neck (distance between the renal arteries and the aneurysm sac) is less than 8mm in length.
· Para-renal: one of the renal arteries comes off the aneurysm itself
· Supra-renal: both the renal arteries and or the mesenteric vessels come off the aneurysm
· Thoraco-abdominal aortic aneurysm (TAAA): This may involve any part of the aorta between the left subclavian artery and the aortic bifurcation. Some of these TAAAS have a AAA component as well.
why do AAAs develop? list 5 theories?
Uncontrolled hypertension · Hypercholesterolaemia · Smoking · Imbalances between proteases and anti-proteases[ --> destruction of collagen and elastin in the media. These enzymes include elastase and metallo-proteinase (MMP) 2 and 9] · Infection: chlamydia pneumonia
classify AAAs accordign to size
small: 4-5.5cm and low risk of rupture 1-2%
large: >5.5cm in diameter with high risk of rupture
Relate aneurysm size and risk of rupture
<4cm 0% per year 4-5cm 0.5 to 5% per year 5-6cm 3 to 15% per year 7-8cm 10 to 20% per year 7-8cm 20 to 40% per year >8cm 30 to 50% per year
clinical approach to aneurysms
asymptomatic
symptomatic
complicated
typical symptoms in patients with AAA
Vague abdominal pain · Recent onset backache · Vomiting (duodenal compression) · Constipation (colonic compression) · Flank pain (ureteric compression) · Chronic venous disease (venous compression)
complications of AAA
acute lower limb ischaemia (macro embolism)
blue toe syndrome ( microembolism)
rupture: free intraperitoneal or contained retroperitoneal or chronic contained leak
aorto enteric fistula
aorta caval fistula