ART management (2013)

Question 1

At what CD4 count should you start ART?

Answer 1

CD4 count < 500

Question 2

Who requires treatment regardless of CD4 count?

Answer 2

co infection with TB, Hep B, serodiscordant couple, pregnancy, children < 5.

Question 3

At what viral load should ripilvirine not be used as a combination pill?

Answer 3

100,000

Question 4

Dolutegravir versus DRv/R in treatment naive patients

Answer 4

Feinberg ICAAC 2013 - dolutegravir is superior.

Question 5

in what cases do you use a nuc sparing regimen and what would you use

Answer 5

severe osteoporosis

Boosted PI + Raltegravir.

Question 6

Which mutation confers resistance to dolutegravir?

Answer 6

Q148. Ok with T66, Y1`43 and N155 (Nicholas IAS 2013)

Question 7

What advantage does TAF compared to TDF

Answer 7

Less renal toxicity and reduction in bone mineral density

Question 8

Which mutation deletion is associated with CCR 5 receptor deficiency

Answer 8

delta 32

Question 9

Which drug regimen is recommended for use of PrEP for IDU -

Answer 9

TDF-FTC