ARRYHTHMIA Flashcards

1
Q

is a problem with the rate of rhythm of the heartbeat(Irregular heartbeat). During an arrhythmia, the heart can beat too fast, too slow, or in irregular rhythm.

A

Arrhythmia

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2
Q

Heartbeat that is too slow

A

Bradycardia

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3
Q

Heartbeat that is too fast

A

Tachycardia

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4
Q

5 elements of cardiac conduction system

A

Sino atrial node
Atrioventricular node
Bundle of His
Purkenji Fibers
Bundle of Branches

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5
Q

It is the impulse that signals the heart to contract

A

Sinoatrial node

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6
Q

P wave

A

Contraction of atria

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7
Q

QRS wave

A

Contraction of ventricles

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8
Q

T wave

A

Repolarization of ventricles

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9
Q

Phase 0 aka

A

Upstroke

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10
Q

Phase 0

A

Opening of Na gated channel

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11
Q

Phase 1 aka

A

Early Fast Repolarization

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12
Q

Phase 1

A

Closing of Na, Opening of K, Cl channel

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13
Q

Phase 2 aka

A

Plateu phase

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14
Q

Phase 2

A

Sustained inward movement of calcium, outward movement potassium

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15
Q

Phase 3 aka

A

Repolarization Phase

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16
Q

Phase 3

A

Sustained opening of K Channel, Closed Ca Channel

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17
Q

Phase 4 aka

A

Resting phase

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18
Q

Phase 4

A

Diastole all channel are closed

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19
Q

Is a rapid heart rate that is caused by electrical impulses that orginate above the hearts ventricls

A

Supraventricular Tachycardia

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20
Q

Supraventricular Tachycardia aka

A

Paroxymal Supraventricular Tachycardia

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21
Q

Most common type of arrythmia

A

Atrial fibrillation

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22
Q

Similar to atrial fibrillation, spread through atria

A

Atrial flutter

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23
Q

It is an uncommon and distinctive form of polymorphic supraventricular tachycardia

A

Torsades de Pointes

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24
Q

An extra or so called accessory pathway exist in the upper and lower chamber of the heart

A

WOFF PARKINSONS WHITE SYNDROME

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25
Q

Class 1

A

Na channel blockers

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26
Q

Class 2

A

Beta blockers

27
Q

Class 3

A

Potassium channel blocker

28
Q

Class 4

A

Calcium channel blocker

29
Q

Class 1A

A

Dysopyramide
Quinidine
Procainamide

30
Q

Class 1B

A

Mexiletine
Tocainide
Lidocaine

31
Q

Class 1C

A

Moricizine
Flecainide
Propafenone

32
Q

Anticholinergic moderate

A

Quinidine

33
Q

Quinidine S/E

A

Cinchonism

34
Q

Cinchonism

A

Blurred vision, Tinnitus, Headache, Psychosis

35
Q

Enhances Digitalis toxicity

A

Quinidine

36
Q

Anticholinergic short half life

A

Procainamide (Pronestyl)

37
Q

Procainamide S/E

A

SLE

38
Q

Drug second choice for most sustained ventricular arrthymias with MI

A

Procainamide (Pronestyl)

39
Q

Anticholinergic Strong

A

Dysopyramide (Norpace)

40
Q

Dysopyramide S/E

A

Negative inotropic effect

41
Q

Decrease action potential duration

A

Class IB

42
Q

Weakly inhibits phase O

A

Class IB

43
Q

Used in Post arrthymia

A

Class IBy

44
Q

Toxic metabolite of Lidocaine

A

Monoethyl Glycine Xylidide, Glycine Xylidide

45
Q

Strongly inhibits Phase O

A

Class IC

46
Q

Use in paroxymal atrial fibrillation

A

Class IC

47
Q

Terminate ventricular tachycardia and prevent ventricular fibrillation after cardioversion

A

Lidocaine

48
Q

Orally active congeger of lidocaine used in ventricular arrythmia chronic pain syndrome

A

Mexiletine

49
Q

Undergo firstpass hepatic metabolism

A

Lidocaine

50
Q

Lidocaine toxicity

A

Neurologic symptoms

51
Q

Orally active weak b blocking activity supraventricular arrythymia

A

Propafenone

52
Q

Phenothiazine derivative orally active withdrawn in US

A

Moricizine

53
Q

Class II

A

Propranolol, Esmolol

54
Q

B adrenoreceptor blockade

A

Propranolol

55
Q

Propranolol duration

A

4-6hrs

56
Q

Propranolol toxicity

A

Asthma, AV blockade, acute heart failure

57
Q

Short acting IV only use for intraoperative

A

Esmolol

58
Q

Class 3

A

Amiodarone (Cordarone)

59
Q

Class 3 halflife

A

40-50days

60
Q

Amiodarone toxicity

A

Hyperthyroidism
Stiffening of the lungs
Corneal deposits
Bluish discoloration of nail

61
Q

Use in serious ventricular and supraventricular arrthymias

A

Amiodarone

62
Q

Investigational

A

Vernakalant

63
Q

Amiodarone derivative reduce mortality

A

Dronedarone