Arrhythmia Surgery Flashcards
“Cut and Sew” MAZE Lesions

Determinants of Cryoablation Lesion Size
- Probe Temperature
- Thermal Conductivity
- Tissue Temperature
Cryoablation Advantages and Disadvantages
Advantages
- Freezing is a safer energy source - preserves ECM structure
Disadvantages
- Risk of coronary stenosis
- Time consuming (1-3min per lesion)
- Less safe/effective on beating heart (thromboembolism/heat sink)
Determinants of Radiofrequency Ablation Lesion Size
- Electrode-Tissue Contact Area
- Interface Temperature
- Current and Voltage (Power)
- Duration
Biopolar Radiofrequency Advantages and Disadvantages
Advantages
- Create trasnmural lesions on the beating heart
- Limits collateral injury
Disadvantages
- Access needed for tissue to be sandwiched between the two poles
Cox-Maze IV Lesion Sets
- Pulmonary Vein Isolation (bipolar RF)
- Right Atrial Lesion Set (beating heart; bipolar RF + unipolar or cryoablation endocardially down to the TV annulus)
- Left Atrial Lesion Set (arrested; amputation of the LAA; bipolar RF to connect the PVV lesions + unipolar or cryoablation endocardially down to the MV annulus)

Pulmonary Vein Isolation Lesion Sets

Rx-free Freedom from Symptomatic AF
Paroxysmal AF
- 6-months - 90%
- 1-year - 90%
- 2-years - 90%
- 10-years - 85%
Persistent AF
- 6-months - 90%
- 1-year - 90%
- 5-years - 80%
Pulmonary Vein Isolation and LA Lesion Sets Without the Mitral Annular Lesion Increase the Risk of…
Atrial Flutter
Freedom from AF with Complete MAZE vs. LA Lesion Sets Only
Freedom from AF
- Complete Cox-MAZE IV - 85%
- LA Lesions Only - 75%
Drug-free Freedom from AF
- Complete Cox-MAZE IV - 80%
- LA Lesions Only - 50%
Freedom from AF for Surgical vs. Catheter Pulmonary Vein Isolation
at 1-year
Surgical - 65%
Catheter - 35%
Indications for Surgical MAZE
- Symptomatic patients with documented AF undergoing concomitant cardiac surgery
- Asymptomatic patients with documented AF undergoing concomitant cardiac surgery if low risk
- Symptomatic patients with documented AF and failed (or not candidates for) catheter ablation
- Symptomatic patients with documented AF with CHADS > 2 but contraindications to anticoagulation, especially if they have already suffered a neurologic event
3 Letter International Pacemaker Code
“Paced” / “Sensed” / “Algorithm” / “Rate Response”

CRT-P ⇒ biventricular pacer
CRT-D ⇒ biventricular pacer-defibrillator
ACC/AHA Guideline Indications for PPM Insertion
Class I (symptomatic…)
- AVB (second or third degree)
- Sinus bradycardia/block/arrest (positive tilt table test SA asystole > 3sec
- Tachy-Brady syndrome
Class II
Symptomatic patients with…
- Bifascicular/Trifascicular block
- Hypertensive carotid sinus syndrome
Asymptomatic patients with…
- Complete AVB
- Mobitz II
- Congenital AVB
- Sinus bradycardia < 40 requiring Rx
- VT requiring overdrive pacing
Class III
- Syncope NYD
Asymptomatic patients with…
- Sinus bradycardia/block/arrest
- BBB
- Mobitz I
AVB
1º AVB
- P-R interval > 200ms
2º AVB
- Mobitz I (Wenckebach)
Progressive P-R interval increase followed by dropped QR
- Mobitz II
Dropped QRS without P-R progression
3º AVB
- Complete AV dissociation
Etiologies of Sinus Node Dysfunction
- CAD
- Cardiomyopathy
-
Reflex Abnormalities
- Carotid Sinus Hypersensitivity
- Vasovagal Syncope
- Micturition-Induced and Deglutition Syncope
“R” - Rate Responsiveness
Increases the lower rate setting in response to increase metabolic demand
Measured by…
- Body Vibration
- Respiratory Rate (minute ventilation)
Componants of DDD Algorithm/Settings
- Lower Rate Limit
- Upper Rate Limit
- AV Delay
HR between rates → 1:1 pacing of the ventricle unless the ventrticle depolarizes prior to the delay length
Atrial HR below lower limit → atrial pacing at the lower limit rate
Atrial HR above upper limit → ventricle paced at upper limit (Wenchebach appearance)
Anticoagulation for AFib Trials
Warfarin vs. DOAC for non-valvular AFib
- RE-LY (2009 NEJM) - Dagatroban
- ROCKET-AF (2011 NEJM) - Rivaroxiban
- ARISTOTLE (2011 NEJM) - Apixaban
MAZE Energy Sources
- Radiofrequency
- Cryoablation
- High-Intensity Focused U/S
- Laser
Normal ECG Intervals
- PR Interval 120-200ms (3-5 small boxes)
- QRS Duration < 120ms (3 small boxes)
- QT < 400ms
Indications for DDD pacing in elderly patients
- Pacemaker Syndrome
- HTN
- CHF
Magnet Mode
VOO
Best PPM mode for Trasnplant Patients with SA Node Dysfunction
AAIR
Treatment of Acute Bradycardia
- Atropine
- Dobutamine
- Isoproterenol
- Temporary Pacing
Anatomical Vascular Approaches to PPM Insertion
- Cephalic Vein
- Axillary Vein
- Subclavian Vein
- External Jugular
- Internal Jugular
Complications of PPM Insertion
Perioperative Complications
- Pneumothorax
- Hemothorax
- Major Vessel Injury (Arterial)
- Lead Displacement
- Venous or Cardiac Perforation
- Air Embolism
- VT/VF
Late Complications
- Infection/Erosion
- Lead Entrapment
- Device Dysfunction
- Lead Fracture (impedance < 300 → insulation #; > 1000 poor conduction)
- Subclavian Crush
- Twiddler’s Syndrome
- Pacemaker-Mediated Tachycardia
Implant Parameters
R-wave amplitude > 5mV
P-wave amplitude > 2mV
Impedance 400 - 1000 ohms
Thresholds < 1.0V at 0.5ms
(No diaphragmatic stimulation at 10V)
Pacemaker-Mediated Tachycardia
PVC conducted retrograde through the AV node causing retrograde depolarization of the atrium sensed by the pacemaker triggering inappropriate pacing of the ventricle at the upper rate limit
Limiting the upper rate limit setting or increasing the postventricular atrial refractory period to 300-350ms after the QRS may correct this
Pacemaker Syndrome
Loss of AV synchrony in VVI mode (contraction of the atrium against a closed AV valve; eleviated in DDD mode)
Sensing Problems
- Undersensing
- Oversensing
- Crosstalk
- Far-Field Sensing
- Exit Block (reduced by steroid-eluting leads)
Mode Switching for Paroxysmal AFib
VVIR → when upper rate limit is exceeded
DDDR → when atrial rate belwo the upper rate limit
Requires
- Bipolar leads
- High sensitivity setting to detect low-amplitude AF
Trials Demonstrating Benefits of ICD Therapy
- AVID
- MUSST
- MADIT-I (EP Inducable VT, with clinical non-sustained VT and PMHx of MI)
- MADIT-II (PMHx of MI and EF < 30%)
- SCD-HeFT
- COMPANION
No Benefit of ICD Therapy
- CABG-Patch (CABG vs. CABG+ICD)
- DINAMIT (ICD Post-MI)
Indications for ICD Implantation
Secondary Prevention
- Clinical VT/VF, EP Inducable VT/VF, Absence of MI, Unsuitable for Rx or Ablation
- Clinical VT/VF, EP Inducable VT/VF, PMHx of MI
Primary Prevention
- ICM, LVEF < 35%, NYHA Class II or III, > 40d post-MI
- ICM, LVEF < 30%, NYHA Class I, > 40d post-MI
- Non-ICM, LVEF < 35%, NYHA Class II or III
Causes of VT Refractory to Defibrillation
- Iatrogenic Pneumothorax
- Myoardial Ischemia
- Electromagnetic Dissociation
- Inappropriate ICD Lead Location
Criteria for Class I Indication for CRT
- LVEF < 35%
- NSR
- Optimal Medical Therapy
- LBBB with QRS > 150ms
- NYHA Class II, III or ambulatory IV