Arrhythmia Flashcards
Arryhtmia
abnormalties in HR
causes of arrythmia
impulse generation, impulse conduction
impulse generation types
triggered, abnormal automaticity
impulse conduction types
re-entry circuits, heart block
classification based on
effect on HR, site of origin
normal pacemaker
SAN
tachyarrhythmia
increase HR
bradyarrhythmia
decrease HR
Abnormal automaticity
SAN overriden by abnormal pacemaker activity in myocardium
causes of abnormal A
ischaemia, hypokalaemia, catecholamine
triggered automaticity
extra depol during non-nodal AP, EAD end of phase 2/phase 4 DAD
triggered A causes
excessive net inward depol current, Ca accumulation in cell
Triggered A in response to:
cardiac glycosides, phosphodiesterase type III inhibitor, catecholamines, hypercalcaemia, ischaemia, class 1A+III AA drugs
re-entry circuits
re-excitation of myocardium by arrival or re-entry of delayed impulse
re-entry circuit requirements
control inexcitable region, zone of slowed conduction, zone of unidirectional block