ARF Flashcards
Respiratory Failure:
A clinical condition in which the _____ system fails to maintain _______.
pulmonary system
adequate gas exchange
Respiratory Failure:
Failure to meet _____, ______, or _____ demand of the patient.
Oxygenation,
Ventilation,
Metabolic
Deficiency in the performance of the pulmonary system usually occurs ____ to another disorder that has ____ the normal function of the pulmonary system.
secondary,
altered
What are the causes of respiratory failure?
- ____
- _____
- _____
- Depressed ventilatory drive
- Failing ventilatory pump
- Gas Exchange organ
Any combination
Respiratory failure can be __
a. Acute
b. Chronic
c. acute-on-chronic
d. All of the above
d. all of the above
Whane PaO2 is lower than 8.0 kPa and PaCO2 is normal this is…
Type 1 Respiratory failure (oxygenation failiure)
When PaO2 is lower than 8.0 kPa and PaCO2 is higher than 6.5 kPa this is….
Type 2 Respiratory failure (ventilation failure)
Type 1 Respiratory failure is classified as…
PaO2 is ____ than 8.0 kPa
PaCO2 is ______ than 6.5kPa
lower
normal
Type 2 Respiratory failure is classified as…
PaO2 is ____ than 8.0 kPa
PaCO2 is ______ than 6.5kPa
lower
higher
Normal value of PaO2?
12-15 kPa
Normal value of PaCO2?
4.5-5.5 kPa
Normal value of pH
7.35 - 7.45
higher =alkalotic
lower = acidotic
Type 1 respiratory failure is caused by diseases that damage ______
the lung tissues
Type 1 respiratory failure is caused by impaired gas diffusion across _______ membrane
alveolar capillary
Pulmonary diseases that can lead to type 1 respiratory failure are…?
Asthma
Pneumonia
Effusion
COPD
Vascular diseases that can lead to type 1 respiratory failure are…?
Pulmonary embolism
Cardiogenic pulmonary
Oedema
CCF (congestive cardiac failure)
What is V/Q ratio?
Ventilation/perfusion
What is considered a normal V/Q ratio?
0.8
Pathphysiologcal processes involved in Acute Resp Failure are:
A_____ H____
V_____ and P_____ mismatch
D______ impairment
Alveolar Hypoventilation
Ventilation and Perfusion mismatch
Diffusion impairment
PROGRESSION OF HYPOXAEMIA 1. 2. 3. 4.
- low O2 at cellular level
- tissue hypoxia (impaired perfusion)
- Lactic acidosis
- multiple organ dysfunction
MECHANISMS UNDERLYING AIRFLOW LIMITATIONS IN COPD
Small Airways disease:
1.
2.
3.
Parenchymal Destruction
1.
2.
Small Airways disease:
- Airway inflammation
- Mucus retention
- Increased Airway Resistance
Parenchymal Destruction
- Loss of alveolar attachment
- Decrease in elastic recoil
Risk factors for COPD Mitigatable: C\_\_\_\_\_ O\_\_\_\_\_ E\_\_\_\_\_ I\_\_\_\_\_\_
Cigarette smoke
Occupational dust and chemicals
Enviromental smoke/tobacco
Indoor and outdoor air pollution
Risk factors for COPD Un-Mitigatable: G\_\_\_\_\_ I\_\_\_\_\_ S\_\_\_\_ E\_\_\_\_ A\_\_\_\_\_\_
Genes
Infections
Socio-economic status
Aging population
Diagnosis of COPD Symptoms: S\_\_\_\_\_\_ C\_\_\_\_\_\_ C\_\_\_\_\_ S\_\_\_\_
PLUS Risk Factors: T\_\_\_\_\_ O\_\_\_\_\_ I\_\_\_\_\_
Tested by S______
Diagnosis of COPD Symptoms: Short of breath Chronic Cough Sputum production
PLUS Risk Factors: Tabacco Occupation Indoor/outdoor pollution
Tested by Spirometry