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Lab Lecture > Areosol Therapy > Flashcards

Areosol Therapy Flashcards

1
Q

Operation of mesh

A

Electric vibrates piezoceramic plate @ freq
of 130khz

1,000 aperture’s

3-4 um

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2
Q

Mesh drug volume?

A

0.1-4 mL

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3
Q

Mesh disadvantages?

A

Costly
Difficult to repair

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4
Q

Principal of ultrasonic nebulizer

A

Piezoelectric principle

Crystal transducer converts electric signals to acoustic vibrations that generates a geyser

Used for bland and med. For med as a stand alone or w/ O2

Not adjustable size

Larger volume : bland
Small volume: drug delivery

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5
Q

Advantages of mesh and ultrasonic

A

Rapid delivery
Low dead vol
Portable
Little effect on density
Uniform
Reduce time
Can deliver undiluted bronchodilator
Does not add extra flow to ventilator

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6
Q

Disadvantages of vibrating mesh and ultrasonic

A

Size, density, and output effected by humidity of gas carrier

Temp might ⬆️ 10 degrees C

High cost

Erratic reliability

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7
Q

Particle size of jet

A

1-5 um

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8
Q

Hold of small jet

A

5-20 mL

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9
Q

Hold for large Jet

A

200mL

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10
Q

Why larger

A

Longer treatment time and larger dose

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11
Q

Vol for small particle Generator

A

2-3L

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12
Q

How long until more than half aerosolize is delivered from jet?

A

10 min

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13
Q

What percentage of deposition from Jet

A

As little as 1, but usually 10-20%

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14
Q

How much more med is delivered with reservoir?

A

5-10%

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15
Q

How much more med is delivered with collection bad

A

30-59%

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16
Q

How much more aerosol is delivered with venting system?

A

50%

17
Q

Other name for venting system

A

Breath enhanced

18
Q

Particle size for ultrasonic and Mesh

A

3-4 um

19
Q

Drug vol for ultrasonic

A

0.1-4 mL

20
Q

MDI particle size

A

1.1 um

21
Q

Vol emitted by MDI

A

15-20 mL

22
Q

Vol emitted by MDI

A

15-20 mL

23
Q

MDI deposition

A

10-25%

24
Q

Spacer reduces risk of pharyngeal impact?

A

10-15 fold

25
Q

How long between MDI actuations

A

15 seconds

26
Q

MDI breath number for Peds

A

5-6

27
Q

What inspiratory flow is needed for DPI

A

30-120L/min

28
Q

How many dosages does a multiple-unit Dose DPI contain?

A

4-8 individual blister packets

29
Q

How many dosages does a multiple Dose drug reservoir DPI contain?

A

120 doses

Lab Lecture (3 decks)

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