Aquifer Flashcards
Ottawa ankle rules
only get ankle XR if pain in malleolar zone and
- bony tenderness along distal posterior edge of either malleolus OR
- unable to bear weight (4 steps unassisted) right after injury and while in ED
Cervical cancer screening guidelines by age group
21-29: screening every 3 years
30-65: can screen every 5 years if co-tested for HPV (preferred) OR every 3 years with cytology alone (acceptable)
Risk groups that need more freq cervical cancer screening
- immunocompromised
- HIV+
- history of CIN 2, 3, or cancer
- exposure to DES in utero
*note cigarette smoking is strongly correlated with cervical dysplasia and cancer
criteria for stopping cervical cancer screening in women >65
adequate screening within the last 10 years, ie 3 consecutive normal pap with cytology OR 2 consecutive normal pap with HPV testing
Screening mammography criteria
Every 2 years for women age 50-74
Screening mammography criteria
Biennially for women age 50-74
What tool can you use to individualize recommendations for mammogram?
Gail criteria
When should Tdap be given in adults?
Tdap should replace a single dose of Td for adults age 19-64 who have not previously received Tdap
Perimenopausal symptoms due to estrogen deficiency
Vaginal dryness; decreased libido
Hot flashes - dress in light layers, use fan, regular exercise, avoid spicy foods and heat, manage stress
Mood swings - esp depression
Osteoporosis screening guidelines
DEXA for >65
for <65 use WHO fx assessment tool to risk stratify. screen if risk of fx >9.3 percent over 10 years.
Osteoporosis risk factors
low estrogen states (early menopause, prolonged premenopausal amenorrhea, low weight)
low physical activity
inadeq calcium intake (eg poor nutrition, alcoholism)
family history osteoporotic fx
personal h/o previous fx as an adult
smoking
white
Adult physical activity guidelines
each week:
150 minutes moderate-intensity exercise OR
75 minutes vigrous exercise OR
combination of both
incorporate strengthening exercises at least twice a week
smoking cessation strategies
set quit date
use nicotine replacement
taking meds
choose a substitute activity (eg walk, chew gum when urge to smoke occurs)
make a list of reasons why imp to quit and keep it handy
keep track of where, when, and why you smoke to help identify triggers to avoid
throw away all smoking things- ashtrays, lighters, etc
join support group
Pap smear adequacy
> 5000 squamous cells
sufficient endocervical cells
Pap smear results
Negative for intraepithelial lesion or malignancy
Evidence of epithelial abnormalities:
- ASC- atypical squamous cells. some abnormal cells, may be infection, irritation, or precancerous
- LSIL- low grade squamous intraepith lesion. may prgress to high grade, but most regress
- HSIL- considered a significant precancerous lesion
- squamous cell carcinoma
Indications for exercise stress testing
asymptomatic males >45 with one or more risk factors )hypercholest, HTN, smoking, FHx premature CAD) may get useful prognostic info from exercise testing
frequency of fasting lipid screen
adults >21 every 4-6 years lipid screening and reassess ASCVD risk
fasting- at least 8 hours after last food intake
Side effects of SSRIs/SNRIs
headache GI- nausea, diarrhea sleep disturbances- drowsiness, insomnia (infrequently) SIADH sexual dysfunction serotonin syndrome
common causes of insomnia in the elderly
envirmonment
drugs/etoh/caffeine
parasomnias-like restless leg
disturbances in sleep wake cycle- jet lag, shift work
psych- depression, anxiety
cardiorespiratory disease (asthma, copd, HF)
pain or pruritis
GERD
hyperthyroidism- elderly often don’t present with the typical sxs
diagnostic criteria for major depressive disorder
depressed mood or anhedonia PLUS at least five of SIGECAPS, present for at least 2 weeks
most common means of suicide in the elderly
drug overdose
labs or studies that can be done to rule out medical causes of insomnia, fatigue, and depression
CBC- anemia and vitamin deficiencies
CMP- electrolyte, renal, hepatic problems
TSH- hypo or hyperthyroidism
ESR- rheumatologic disease
ECG if pt using drugs that might alter cardiac conductivity such as TCAs
SAFE-T (Suicide Assessment Five Step Evaluation and Triage) components
- Risk factors
- Protective Factors
- Suicide inquiry- thoughts, plans, behaviors, intent
- Risk level/intervention
- Document- risk level and rational, trreatment plan to address/reduce current risk, firearms instructions if relevant, followup.
adult depression screening
PHQ-2:
over the past 2 weeks, have you often been bothered by
- Little interest or pleasure in doing things, or
- Feeling down, depressed, hopeless
For each question the patient can answer:
Not at all (0 points) Several days (1 point) More than half the days (2 points), Nearly every day (3 points).
(if positive, follow with PHQ-9)
Dementia screening tool
Mini-Cog (faster, more sens and specific than MMSE)
risk factors for elder abuse:
- Dementia.
- Shared living situation of elder and abuser (except in financial abuse).
- Caregiver substance abuse or mental illness.
- Heavy dependence of caregiver on elder. Surprisingly, the degree of an elder’s dependency and the resulting stress has not been found to
predict abuse. - Social isolation of the elder from people other than the abuser.
firstline therapy for insomnia in adults
CBT
-sleep restriction therapy- reduce in bed time to average number of hours patient has actually been able to sleep over the last two wks (rather than time in bed awake). as sleep efficiency improves, increase time allowed in bed 15-20 min every five days until achieve optimal sleep time
-sleep compression therapy- decr amt of time spent in bed to gradually match total sleep time rather than making and immediate substantial change
pharmocotherapy for insomnia
*all drugs a/w side effects esp prolonged sedation and dizziness, that can result in risk of injuries and confusion
Benzo Receptor Agonists (zolpidem, eszopiclone) - improve sleep onset latency, total sleep time, and wake after sleep onset
TCAs - doxepin 3-6mg is the only suggested agent in this class
Orexin receptor antagonist (suvorexant)- improved sleep onset and/or sleep maintenance
Medical conditions associated with depression (causes it or comorbid at higher rates)
Hypothyroidism (check TSH)
Parkinson’s (is an early feature; pts with depression who start developing movement prob should promptly be evaluated to r/o)
Dementia (MMSE)
6 signs of limb-threatening injury
6 P’s
pain pallor pulselessness paresthesia perishing cold (unable to regulate body temp) paralysis
Earliest sign of compartment syndrome
pain, esp disproportionate
Most reliable sign of compartment syndrome
paresthesias (skin sensation such as burning, prickling, itching, tingling)
Most common mechanism of ankle injury
combination of planter flexion and inversion
Most often damaged ankle ligaments
the lateral stabilizing ligaments
- anterior talofibular
- calcaneofibular
- posterior talofibular (strongest, rarely injury in inversion)
Most easily injured ankle ligament
anterior talofibular
ankle anterior drawer test assesses __.
anterior talofibular ligament
ankle inversion stress test assesses __
calcaneofibular ligament
Mechanism of medial ankle sprain
excessive eversion and dorsiflexion
medial ankle sprains are uncommon because of __
bony articulation between medial malleoulus and talus
Grade I ankle sprain
stretching or small ligament tear
slight to no functional loss
no mechanical instability
no excessive stretching or opening of the joint with stress
Grade II ankle sprain
incomplete ligament tear moderate functional impairment some loss of motor function mild to moderate instability stretching of joint with stress but with a definite stopping point
Grade III sprain
complete tear and loss of ligament integrity
severe swelling and ecchymosis
unable to bear weight
mechanical instability
significant stretching of joing with stress, NO definite stopping endpoint
Cross legged test detects ___ and is performed by __.
high ankle sprains (syndesmotic injury between tibia and fibula)
having patient cross their legs with injured leg resting at midcalf on the knee
Pain control for ankle sprains
FIRST check for history of problems with ulcers or anti-inflammatory drugs
Patients can take 2 or even 3 ibuprofen at a time but be sure to eat snack or meal beforehand. Take up to three times a day if needed.
Ankle strengthening exercises
eversion and inversion against fixed object for 10 sec
planterflexion and dorsiflexion against fixed object for 10 sec
can progress to resistance band
TMP-SMP can be prescribed for uncomplicated UTI but consider other options if greater than __ percent resistance
20%
Ottawa rules for foot radiography
pain in the midfoot region AND
1) bony tenderness at navicular bone or base of 5th metatarsal
OR
b) unable to bear weight four steps right after injury and in the ED
list examples of conditions that can cause palpitations in the follow categories:
Cardiovascular Psychiatric Medications Substances Endocrinologic Hematologic Infectious
cardio- arrythmia, cardiomyopathy, hypovolemia
psych- anxiety, panic attacks
meds- caffeine, stimulants, theophylline, albuterol
substances- tobacco, caffeine, alcohol intox or withdrawal, cocaine
endocrine- hyperthyroidism, pheo, hypoglycemia
heme- anemia
infectious- febrile illness
Many typical symptoms of hyperthyroidism are absent in patients age __. Instead they may present with __
> 70 years
sinus tachy and/or fatigue
afib or weight loss with no other symptoms
mildly elevated TSH / normal T4
subclinical hypothyroidism
inappropr normal TSH / high T4
pituitary adenoma
or thyroid hormone resistance
decr TSH / normal T4, high T3
T3 toxicosis
decr TSH / decr T4
central/pituitary hypothyroidism (TSH and/or TRH deficiency)
Graves disease cause _% of hyperthyroidism
60-80%
How to elicit lid lag
move finger SLOWLY from upper to lower field of vision. upper eyelid lags behind the upper edge of iris as eye moves down.
if move finger too fast, may miss it!
Graves disease antibodies
anti thyrotropin receptor (TRAb) - TSH receptor
methimazole vs RAI treatment
methimazole takes months to take effect, pts have to be on it for many years. appropriate dose fluctuates so must have freq bloodwork to adjust. more likely to have sxs as fluctuations are hard to predict.
RAI concentrated in thyroid has very few side effects. most get low thyroid but easy to manage once find apprp dose, only need blood leveles once or twice a year.
causes of hyperthyroidism with low RAIU
subacute thyroiditis silent thyroiditis iodine induced exogenous L-thyroxine struma ovarii amiodarone
microvascular complications DM
retinopathy
nephropathy
neuropathy- sensory, motor (ankle jerk reflex), autonomic (sex, gastroparesis)
macrovascular complications DM
CAD
CVA
PAD
goal BP in diabetics with HTN
<130/80
start statin for DM with LDL __
> 70
In pts with ASCVD or CKD, what are the best second line DM agents in addition to metformin and why?
GLP-1 receptor agonist
or SGLT2 inhibitor bc of demonstrated cardiovascular risk reduction
Diagnostic criteria for DM
- random BG >=200 plus symptoms of hyperglycemia (eg polyuria, unexplained weight loss) or hyperglycemic crisis
- fasting plasma glucose > 126
- Hgb A1c >= 6.5%
- two hour plasma glucose >=200 during OGTT
* fasting glucose, OGTT, and A1c need to be confirmed on a different day unless pt has unequivocal sxs of hyperglycemia
Three fundoscopic findings in severe diabetic retinopathy
Hallmark of proliferative retinopathy
retinal hemorrhage- dark blots w indistinct borders indicating partial obstruction and infarction
cotton wool spots- white spots with fuzzy borders indicating areas of previous infarction
microanuerysms- punctate dark lesions indicating vascular dilatation
neovascularization- hallmark of proliferative retinopathy. growth of new vessels prompted by retinal vessel occlusion and hypoxia
DM optimal blood glucose
fasting: 80-120
postprandial 1-2h after meal: <180
__ is the single greatest contributor to death in the US
smoking
__ is the largest risk factor for cardiovascular mortality in the US
HTN
Majority of deaths from DM are from __ and __
increase in cardiovascular disease; chronic renal failure
Half life of warfarin and implications
40 hours
takes 5-7 days to reach steady state
when adjusting warfarin dosage, should wait at least this long before rechecking INR, as checking sooner can lead to overreactions and great swings in INR
Course of action when goal INR is substantially overshot
Hold warfarin and give oral dose of Vitamin K
Grade 1 ulcer
diabetic ulcer, superficial
Grade 2 ulcer
ulcer extension - involving ligament, tendon, joint capsule, or fascia
Grade 3 ulcer
deep ulcer with abscess or osteomyelitis
Grade 4 ulcer
gangrene forefoot (partial)
Grade 5 ulcer
extensive gangrene of foot
management Grade 1-2 ulcer
outpatient- extensive debridement, local wound care, relief of pressure. tx for infection if there is significant erythema and/or purulent exudate
Grade 3 ulcer management
eval for possible osteomyelitis and PAD. both of these conditions may need to be addressed before ulcer resolves. typically need at least brief hospitalization to address
Grade 5 ulcer management
emergent hospitalization and surgical consultation, often resulting in amputation
Requirements for treating DVT outpatient
Patient:
HD stable
Good renal function
Low risk for bleeding
Home environment stable and supportive, with access to INR monitoring (if using warfarin as anticoagulant)
advantages of LMWH over unfractionated heparin for DVT therapy
Longer half-life, can give subQ once or twice a day
Don’t need lab monitoring
Thrombocytopenia less likely (though may still need periodic platelet monitoring)
Bleeding complications less common
Fixed dosing
Can use outpatient
one advantage of unfractionated heparin over LMWH
it can be immediately shut off and reversed in case of bleeding due to its very short half life. HENCE, choose this in patient with a significant bleeding risk (eg recent admit for GI bleeding)
when would you choose unfractionated heparin over LMWH for DVT therapy?
patient with a significant bleeding risk (eg recent admit for GI bleeding)
What three agents can be used to treat DVT after stabilization?
- warfarin
- Factor Xa inhibitors (fondaparinux, rivaroxaban, apixaban)
- Direct thrombin inhibitor (dabigatran)
pros/cons of warfarin
pros: cheap, providers familiar with it
cons: highly variable dosing range, need for freq lab monitoring, lots of interactions with other meds
pros/cons of Factor Xa inhibitors
pros: doesn’t need weekly lab monitoring, fewer bleeding complications than warfarin and LMWH
cons: expensive, hard to reverse anticoagulation if there’s a bleed
*can’t use in pregnant pts or renal disease
pros/cons of direct thrombin inhibitor ie Dabigatran
pros: doesn’t need lab monitoring. advantage of Xa inhibitors b/c has a reversal agent (idarucizumab) that can be used in cases of serious bleeding
* can’t use in pregnant pts or renal disease
3 overarching goals of DVT therapy
- immediately stop growth of thromboemboli (heparin)
- promote thromboembolic resolution
- prevent recurrence
When is extended anticoagulation indicated after a DVT or PE?
active cancer (no scheduled stop date)
When are patients anticoagulated indefinitely after DVT or PE?
pts with inherited coagulation disorders
Which pts are likely to benefit from screening for inherited thrombophilia?
- initial thrombosis prior to age 50 without obvious risk factor
- FHx VTE
- recurrent venous thrmbosis
- thrombosis in unusual vascular beds eg portal, hepatic, mesenteric, cerebral veins
main use of D-dimer
exclude thromboembolic disease where the probability is LOW
test with best sensitivity and specificity for DVT
venous doppler lower extremity
Wells criteria for DVT
- active cancer (ongoing tx, within 6 months, or palliative)
- paralysis, paresis, or recent plaster immobilization of the legs
- recently bedridden for >3 days or major surgery within 4 weeks
- localized tenderness along distribution of deep venous system
- entire leg swollen
- calf swelling >3cm compared to asymptomatic leg (measured 10cm below tibial tuberosity)
- pitting edema greater in symptomatic leg
- collateral superficial veins (non vericose)
Wells criteria cutoffs for DVT probability
0: low prob
1-2: moderate
3 or more: high
Differential for unilateral LE edema
lymphedema cellulitis DVT venous insufficiency PAD
5 systems that can get end organ disease from HTN
Heart- LVH, angina or MI, HF Brain- CVA, TIA Kidneys- chronic renal failure Blood vessels- peripheral vascular disease Eyes- retinopathy
what qualifies as family history of premature CVD
men <55
women <65
secondary causes of HTN
- OSA
- primary aldosteronism
- renovascular disease
- renal parenchymal disease
- drug/ETOH induced (NSAIDS, sympathomimetics, cocaine)
- pheochromocytoma
- aortic coarctation
- thyroid
- primary hyperparathyroidism
- cushing’s
Most adults can start at __mg thiazide for BP.
Elderly adults should be started at __ or __mg due to risk of ___.
25mg
6.25; 12.5; hypotensive episodes or electrolyte abnormalities
weight loss reduces BP by __
1 mmHg per kilogram of loss
What is DASH eating plan?DASH eating plan reduces BP by _
diet rich in fruit, veg, low fat dairy, with reduced saturated and total fat
11 mmHg
Dietary sodium reduction by __% (about __mg per day) reduces BP by __
25%; 1000mg per day
4-6 mmHg
(no added sodium)
specific measures to reduce dietary sodium
- eat fresh foods
- check labels and ensure “no added sodium”
- minimize adding salt to food at table
- rinse beans
-moderation of ETOH consumption can reduce BP by _
max daily consumption for men and women?
6 mmHg
no more than 2 drinks per daily for men / 1 drink per day in women and lighter weight
(2 drinks = 24oz beer, 10oz wine, 3 oz 80-proof whiskey)
increasing dietary potassium can improve BP by __
good sources of K?
4-5mmHg
fresh fruits and veg, low fat dairy, some fish and meats, nuts, soy products
aspirin should be initiated in pts with HTN age ___ who have ___% ASCVD risk and what 3 other factors?
50-59
greater than 10% ASCVD
- no increased risk bleeding
- life expectancy at least 10 years
- willing to take asa at least 10 years
which antihypertensives should be avoided in pregnant women or reprod-age not on contraception?
ARBs
4 chest pain characteristics that decr likelihood of ACS
4 P’s
- pleuritic - worsened by respiration
- pulsating
- positional
- reproduced by palpation
stabbing pain
5 possible causes pleuritic CP
PE, PTX, viral or idiopathic pleurisy, PNA, pleuropericarditis
list 6 independent risk factors for coronary heart disease
- HDL <40
- DM
- Smoking
- history premature CHD in a first degree relative
- sedentary lifestyle
- obesity
PQRST mnemonic for CC like chest pain
Provocation/Palliation Quality Region/Radiation Severity Timing Symptoms associated
Differential for palpitations
Dysrhythmia
valvular heart disease
coronary heart disease
hyperthyroidism
anxiety/panic disorder
vasomotor symptoms of menopause
anemia
drugs - caffeine, etoh, tobacco, street drugs…low threshold for urine drug screen
Rx drugs- sympathomimetics, vasodilators, anticholinergics, beta blocker withdrawal
4 items that can suggest cardiac cause of palpitations
- duration greater than 5 min
- description of irregular beat (ex pt can tap it out with fingers)
- previous history of heart disease
- male sex
history of palpitations during __ or __ increase likelihood that arrythmia is cause
sleep; work
Non-MSK causes of back pain
- Neoplastic
- Inflammatory (RA)
- Visceral (endometriosis, prostatitis, kidney stone)
- Infection (discitis, Herpes Zoster, osteomyelitis, pyelo, spinal or epidural abscess)
- vascular (aortic aneurysm)
- Endocrine (hyperparthyroid, osteomalacia, osteoporosis, Paget dz)
Red flags serious illness or neuro impairment with back pain
- fever
- unexplained weight loss
- pain at night
- bowel or bladder incontinence
- neurologic sxs
- saddle anesthesia
Disc herniation is classically exacerbated by __ and relieved by __
exac sitting or bending; relieved by lying or standing
increased pain with coughing and sneezing suggests __
disc herniation
Inidications of imaging for back pain
- progressive neuro deficits
- not responding to conservative treatment
- red flags
Back pain CANCER red flags
- h/o cancer
- > 10kg unexplained weight loss within 6 months
- age >50 or <17
- pain persists for more than 4-6wks
- night pain or Pain at rest
back pain INFECTION red flags
- persistent fever >100.4
- h/o IVDA
- recent bacterial infection, particularly bacteremia (UTI, cellulitis, PNA)
- immunocompromised (chornic steroid use, DM, HIV)
red flags CAUDA EQUINA SYNDROME
- urinary incont or retention
- Anal sphincter tone decr or fecal intont
- saddle anesthesia
- BL LE weakness or numbness
- progressive neuro deficits
red flags SIGNIFICANT herniated nucleus pulposus
- major muscle weakness (3/5 strength or less)
2. foot drop
red flags VERTEBRAL FX
- prolonged corticosteroid use
- mild traumage age >50
- age >70
- h/o osteoporosis
- recent significant trauma any age (MVC, fall from substantial height)
- previous vertebral fx
Acute sciatica is __ lasting up to __ weeks. It can be caused by a variety of conditions such as _
lower back pain with radiculopathy below the knee; 6 weeks
disk herniation, lumbar spinal stenosis, facet joint osteoarthritis, spinal cord infection or tumr, spondylolisthesis
Risk factors for LBP
- prolonged sitting (truck driving, desk jobs)
- deconditioning
- suboptimal lifting habits
- repetitive bending and lifting
- spondylosis, disc-space narrowing, spinal instability, spina bifida occulta
- obesity
- low education a/w prolonged illness
- psychosocial- anxiety, depression, life stressors
- occupation-job dissatisfaction, incr manual demands, compensation claims
Most low back pain resolves within ___
one month
Back exam should be performed sequentially in what positions
- standing
- sitting
- supine
Difficulty with heel walk associated with __ disc herniation
L5
*note: expect normal gait even with disc herniation
Difficulty with toe walk associated with __ disc herniation
S1
Stoop test - what is it and what does it test?
Have patient go from standing to squatting
Pts with central spinal stenosis- squatting will reduce the pain
Restricted and painful lumbar flexion suggestive of __ (3)
herniation
OA, or
muscle spasm
pain with lumbar extension suggestive of _
spinal stenosis or degenerative disease
AHCPR guidelines for back XR
- h/o trauma
- h/o cancer
- F/C/weight loss
- strenuous lifting in pt with osteoporosis
- osteoporosis
- prolonged steroid use
- age <20 or >70
- pain worse when supine or severe at night
- spinal fracture, tumor, or infection
Why are Lumbar spine films not so great
lack specificity.
Pts with symptoms and pathology may have normal looking XR / asymptomatic pts may have abnormal XRs
MRI indicated for back pain if
- worsening or unremitting neuro deficit or radiculopathy
- progressive major motor weakness
- cauda equina compression
- suspected systemic disorder (mets or infectious)
- failed 6 weeks conservative care
Explain to pt why, in the absence of red flags or findings suggestive of systemic disease, imaging is not indicated until 4-6 weeks of conservative treatment ?
- Tests will not help you feel better faster
Most people with lower-back pain feel better in about a month, whether or not they have an imaging test.
People who get an imaging test for their back pain do not get better faster. And sometimes they feel worse than people who took over-the-counter pain medicine and followed simple steps, like walking, to help their pain.
Imaging tests can also lead to surgery and other treatments that you do not need. In one study, people who had an MRI were much more likely to have surgery than people who did not have an MRI. But the surgery did not help them get better any faster.
- Imaging has risks
- Imaging can be expensive
Spine XRs expose patient to radiation. Esp concerning in young women because radiation exposure to ovaries in a single L spine radiograph equals getting daily CXR for more than a year
CT expose pts to contrast that have renal tox and even higher doses of radiation. Routine imaging not associated with better outcomes. May find abnormalities unrelated to back pain, can cause anxiety and could lead to more testing and possibly unnecessary intervention.
Most neuropathic back pain is due to impingement of __ , __, __ nerve roots. Hence focus on reflexes, muscle strength, sensation of _
L4, L5, S1
patellar reflex (L2-4) achilles reflex (S1))
strength
- hip flexion and adduction (L2, 3, 4), abduction (L4, 5, S1)
- knee flexion (L5, S1, S2) and extension (L2, 3, 4)
- ankle dorsiflexion (L4, 5) and plantar flexion (S1, S2)
sharp and light touch along great toe (L5), lateral malleoulus and posterolateral foot (sS1)
SLR pain earlier than __ degrees suggestive of malingering.
30
how can you distinguish between tight hamstrings and a sciatic nerve problem?
raise leg to point of pain, lower slightly
dorsiflex foot
if no pain with dorsiflection, pt has tight hamstrings
normal leg can be raise __ degrees
80
what is positive passive SLR
pain radiating down posterior/lateral thigh past knee
How is FABER test performed
What is a positive test
flex hip and place foot on opposite knee
apply pressure on tested knee while stabilizing opposite hip
positive if pain at hip or sacral joing, or leg can’t lower to the point of being parellel to opposite leg
3 components of conservative therapy for LBP
- pharmacologic- NSAID and/or muscle relaxant
- local heat/cold therapy
- activity- stay active / PT
Treatment after adequatee trial of conservative therapy for 5 weeks
if pain for 5 weeks with progression of neuro deficit and poor pain control ,refer to spine surgeon for consult
if no red flags, could continue conservative therapy. however if patient already getting PT, more PT unlikely to help
some evidence that acupuncture can help in LBP
when and what labs should you order for LBP?
labs generally not needed
CBC and ESR if suspect tumor or infection
Noble’s test- how is it performed and what does it diagnose?
iliotibial band tendonitis
Pt lays supine and repeatedly flexes and extends knee while physician monitors lateral femoral epicondyle with their thumb. pain usu worse when knee flexed at 30 degrees
OA often affects __, ___, and ___
knees, hips, back
RA typically affects __ or more joints, often including __ and __
3
hands, feet
Patellar apprehension test- how to perform and what does it diagnose
detects patellar subluxation (incopmlete or partial kneecap dislocation)
positive if pain or giving away sensation when attempting to translate patella laterally
IF concerned about septic arthritis or acute inflammatory arthropathy of knee, what labs should you check
CBC with diff
ESR/CRP
arthrocentesis fluid for cell count with diff, glucose, protein, bacterial culture and sens, polarized light microscopy
Simple knee joint effusion produces __ colored fluid. Can occur in what conditions
clear, straw-colored
OA, degenerative meniscal injuries
Bloody knee aspirate can be associated with __ or ___
knee sprain (ie ACL, PCL) acute meniscal tear
Knee aspirate with blood and fat globules caused by __
osteochondral fracture
If considering RA as cause of knee pain, what labs/tests should you get
RF in blood (not sensitive but has high PPV)
Hand XR can identify erosions and soft tissue swelling
Initial management of OA
Exercise / PT! guidelines strongly recommend
Weight loss if obese
One time ultrasound screen for AAA recommended in what group
MEN age 65-75 with history of smoking
Lachman test assesses __
stability of ACL
Tinel’s test
tap over median nerve to reproduce sxs
Phalen’s test
flex wrist by having pt put dorsal surfaces of hands together for 30-60 seconds to reprod sxs
Durkan’s sign
compress carpal tunnel for 30 seconds to reproduce sxs
*most sensitive and specific out of three physical exam tests
3 Grade A ways to manage OA pain
EXERCISE- eg walking, cycling, tai chi
Acetaminophen (preferred over NSAIDs due to better safety and side effect profile)
NSAIDs (diclofenac may be the most effective NSAID) (weaker evidence for topical diclofenac) (NSAIDs also increase risk of MI)
Tramadol- modest benefit but use is limited by side effects. can lower seizure threshold in pts with epilepsy
Intra-articular knee corticosteroid injection should be considered if _
guidelines for how often you can use injection?
knee joint is inflamed (swelling and pain)
no more than 3 a year
no more than one a month
Grade B; short term benefit with few adverse effects
when could you get a knee XR to assess osteoarthritis?
- diagnosis uncertain
- to evaluate severity/location of OA
- no improvement with conservative treatment
what knee XR views should you get to assess OA
AP
lateral
standing
Merchant’s view (top view with knee at 45 degrees to show alignment of patella in groove of femur)
4 major radiographic features of OA
- joint space narrowing
- subchondral sclerosis
- osteophytes (bone spurs)
- subchondral cysts (fluid filled sacs in bone marrow)
**knee XRs are insensitive for detecting early OA and dont correlate well with degree of symptoms
on knee XR:
____ correlate best with pain
____ best predicts disease progression
patellofemoral and tibiofemoral joint osteophytes- pain
joint space narrowing- progression
Diagnostic test of choice for carpal tunnel syndrome
nerve conduction study - not typically needed to diagnose if HP suggests carpal tunnel
should only be done if sxs fail to improve with conservative tx, motor dysfunction, or thenar atrophy on exam
Must educate pt on expectations for pain control and attainable goals. Should not expect to be entirely pain free. Should judge pain control based on __
ability to perform activities of daily living
set attainable functional goals
List 4 chronic pain meds
opioids- controversial, uncertain benefits for long term control, serious adverse effects
TCAs- helpful esp for neuropathic pain, and aids sleep interrupted by pain. limited by anticholinergic side effects. CI in severe cardiovasc disease/conduction prob
SSRIs/SNRIs- effective in certain types of pain like fibromyalgia and diab neuropathy.
Anticonvulsants- gabapentin and pregabalin for neuropathic pain
Pts with chronic pain should be screened and treated for __
comorbid depression
there are high rates of depression among pts with chronic pain.
colon cancer screening recommended for pts age __
50-75
mammogram screening recommended __ (frequency) for pts age ___
once every two years
50-74
Community residents aged ___ should be encouraged to ___
exercise to prevent falls
options for pts who fail conservative therapy including acetaminophen for knee pain
NSAID but consider GI tox, renal and BP effects esp in older pts
screen for depression
Tramadol if all else fails
what condition should you ask about before prescribing tramadol
seizures
can lower seizure threshold
differential diagnosis for knee pain
- patellofemoral pain syndrome
- iliotibial band tendonitis
- sprain ACL, PCL, MCL, LCL
- meniscal tear
- septic arthritis
- Lyme
- OA
- RA, psoriatic. SLE
- gout/pseudogout
- Baker’s cyst
USPSTF recommendations for chlamydia screening
All sexually active women 24 and younger
Sexually active women 25 and older who are at increased risk
Risk factors for chlamydial infection
- h/o chlamydia
- new or multiple sex partners
- inconsistent condom use
- exchanging sex for money or drugs
All women (normal risk) planning or capable of pregnancy should take supplement with ___ (amount) folic acid
400-800 mcg
Women with __ should take 1mg folic acid
DM or epilepsy
Women who’ve had a child with previous neural tube defect should take ___mg folic acid
4
Preconception counseling should include screening for what diseases
- sickle cell
- thalassemia
- tay sachs
- CF (fam hx)
- nonsyndromic hearing loss (connexin-26) (fam hx)
Preconception infectious disease screening/immunizations/counseling
- HIV, syphilis
- Hep B vaccination
- preconception vaccines (rubella, varicella- they’re live)
- Toxoplasma counseling (avoid cat litter, garden soil, raw meat)
- CMV, paro B19- frequent handwashing, universal precautions
Preconception lifestyle counseling
- exercise
- avoid hyperthermia (hot tubs, overheating)
- caution against obesity or underweight
- screen domestic violence
- assess risk nutritional deficiencies (vegan, pica, milk intol, Ca or Fe def)
- avoid overuse vitamine A and D
- limit caffeine to 2 cups coffee a day
Pelvic exam signs of pregnancy
- softening of cervix
- softening of uterus
- blue-purple cervix and vaginal walls (hyperemia)
Naegele’s rule to calculate estimate due date
first day of LMP
add 1 year, subtract 3 months, add 1 week
First sign of significant bleed
increased pulse
bleeding can continue for a while before blood pressure drops
Ectropion is when ___ and is common in __
central part of cervix looks red from protrusion of endocervical epithelium protruding thru cervical os
women taking OCPs
When should EGA/EDD based on LNMP be changed to reflect ultrasound calculations?
First and second trimester
if ultrasound shows EGA/EDD >7 days calculated from LNMP
adolescent interview mnemonic
Home Education/employment Eating Activities Drugs Sexuality Suicide/depression Safety/violence
Three ways to deal with inevitable abortion
Expectant - watch and wait. takes up to a month, delays emotional closure
Surgical - indicated for unusually heavy bleeding or patient preference. CONTRAindicated in pelvic infection
Medical- vaginal misoprostol (cytotec) and generally takes 3-4 days.
What should you not forget to do in an abortion?
confirm Rh negative patients have gotten RhoGam
Initial pregnancy labs (6)
CBC- anemias (nutritional, congenital) and platelet disorders
Blood type to detect Rh antibody presence
Rubella antibody test
Hep B surface antigen test
RPR for syphilis
HIV status
Labs to investigate first trimester vaginal bleeding
CBC - for hgb/hct
wet mount for trichomonas, PCR for GC chlamydia (all STIs can cause vaginal bleeding)
progesterone - good PPV and NPV at extremes of reference range. in between 5-25 doesn’t help distinguish IUP from ectopic
quantitative beta-hCG
progesterone level __ highly assoc with sustainable IUP
> 25
progresterone level __ highly associated with evolving miscarriage or ectopic pregnancy
<5
may be not be able to detect IUP until b-hCG reaches __
1500-1800 (transvaginal)
detection of IUP by transabdominal U/S needs b-hCG level __
> 5000
in normal pregnancy, b-hCG doubles every __ in the first __ weeks of gestation
48 hours; 6-7 weeks
molar pregnancies may have b-hCG around ___
10,000
what is threatened abortion?
bleeding before 20 weeks
inevitable abortion
dilated cervical os. everything still in uterus
incomplete abortion
some but not all intrauterine contents expelled
missed abortion
fetal demise without cervical dilation or uterine activity
often found incidentally on U/S without presentation of bleeding
septic abortion
with intrauterine infection- usu have abdominal tenderness and fever
complete abortion
products of conception completely expelled from uterus
three most common causes of bleeding in early pregnancy
- spontaneous abortion
- ectopic
- idiopathic bleeding in a viable pregnancy
management of stable patient who complains of vaginal bleeding in pregnancy
serial quant b-hCG and ultrasounds
uterine fundus rises 1cm for every week of pregnancy after __ weeks
20
when should RhoGam be given for Rh neg pts?
- 24 weeks
- 72h after gestation
- with any episodes of vaginal or intrauterine bleeding
quad serum screening measures __ and is performed at ___ weeks
AFP, hCG, unconjugated estriol, inhibin A
(abnml levels may indic incr risk NTD, trisomy 21, 18)
15-21 weeks
dietary advice for n/v in pregnancy
- frequent small melas
- avoid foods and textures that cause nausea
- solid foods should be bland, high in carbs, low fat
- salty foods can usu be tolerated in morning
- sour/tart liquids often tolerated better than water
Screening for gestational diabetes should be performed at ___ weeks with ___
24-28 weeks
1 hour glucose tolerance test
symptoms of severe preeclampsia
- visual disturbance
- severe HA
- RUQ or epigastric pain
- N/V
- decr UOP
if 1 hour GTT elevated, get 3h.
components of 3 hour GTT and what diagnoses gestational diabetes
fasting, 1, 2, 3 hours postprandial
above cutoff for at least two measurements
postpartum blues typically last __
2 weeks