AQA Biology Non-included Questions Flashcards
C14 - Diagram: part of the retina in the human eye
when light falls on cells 1 and 2, only one spot of light is seen. But when light falls on cells 2 and 3, two spots of lights are seen.
- cells 1 and 2 share neurone but 2 and 3 have separate neurones
C14 - why is it that when cell 3 receives one unit of light energy no light is seen, but when one unit of light energy is received by 3, cells light is seen (3)
- 1 unit of light energy on one cell is below the threshold
- 3 units of light energy is above the threshold so gives sufficient depolarisation
- no impulses in sensory neurone (3>impulses)
- through spatial summation a sufficient neurotransmitter is released
C14 - cells of the same type as cells 6 and 7 are found in large numbers at the fovea, this results in colour vision with high visual acuity
- cone cells are sensitive to different wavelengths/different frequencies of these waves cause different colours
- Impulses along separate neurone from each receptor cell/each receptor cell connects to separate neurones
C14 - explain why an increased cardiac output is an advantage during exercise (3)
during exercise:
- more energy is released
- more respiration
- more actively respiring muscles
A higher cardiac output:
- increases O2 supply to muscles
- increases glucose supply to muscles
- lactate removal
- increases heat removal from muscles (for cooling)
C14 - Explain how nervous control in human can cause increased cardiac output during exercise (4)
- coordination via medulla located in the cardiac centre
- Increased impulses along sympathetic nerve
- to the SA node
- more impulses= increased rate of SA node to increase rate of firing
C14 - Points A and B show when the atria and ventricles contract at which point was the ventricle contracting and why
B
- 2nd contraction
- occurs immediately after the atrium contraction
- larger more force, more pressure
C14 - Addition of acetylcholine in the experiment mimics the effect of which branch of the autonomic nervous system
parasympathetic nervous system
C14 - If acetylcholine reduces the heart rate and has no effect on the stroke volume. What effect will it have on the cardiac output
- Cardiac output is reduced
- Q= HR x SV
- if heart rate is reduced then so is the cardiac output
C4 - DNP prevents Oxidative phosphorylation. when treated with DNP the sodium potassium pump no longer works. Why is this
- lack of ATP produced from oxidative phosphorylation
- pump = is active transport so requires energy from ATP
- if there is a lack of it then sodium ions cannot be transported out and the concentration gradient remains the same
C4 - Why is it that sodium ions and amino acids are not absorbed from the lumen of the small intestine in the presence of DNP
- concentration of Na ions inside the cell aren’t transported so there is no concentration gradient
- as a result no facilitated diffusion of sodium ions from the lumen
- amino acid absorption requires diffusion of sodium ions so therefore cannot enter via co-transport
C4 - By what mechanism would amino acids leave the epithelial cell
facilitated diffusion
C7 - use the cohesion-tension theory of water movement through a plant and why the diameter of the trunk is smallest at midday (6)
- diameter of trunk minimal at warmest/brightest time of day - (midday is the warmest and brightest)
- Stomata open in light = more water loss
- Water evaporates even more when warm
- Hydrogen bonds occur between water molecules (cohesion)
- Then adhesion between water molecules and walls of xylem vessels
- Xylem is pulled inwards by the faster flow of water and pulled in by tension
C7 - Three ways in which the leaves of xerophytic plants may be adapted to reduce water loss (3)
- thick cuticle (wax layer)
^waterproof and impermeable - reduced number of stomata
^reduced surface area for water loss - small leaves
^reduced surface area for water loss
C15 - Why are the arrangement of actin and myosin filaments visible under the electron microscope but not under the optical microscope
electron microscope has greater resolution
- able to tell two close objects apart better
- electrons have a shorter wavelength
C16 - When would glucagon and insulin be released
Glucagon: blood glucose levels are below norm
Insulin: blood glucose levels are above the norm
C21 - Many diabetics require regular injections of insulin.
Describe how bacteria can be genetically modified to produce human insulin
1) cut out insulin gene and cut open plasmid with restriction enzyme
2) use same restriction enzyme on second DNA
3) when cut there are complimentary sticky ends
4) DNA ligase used to join two DNA molecules
5) modified plasmid taken up by bacteria
C21 - The fragment of DNA containing the normal allele and the fragment containing the beta-thalassaemia allele moved the same distance on the gel
Explain why
- cut at the same base sequence
- same enzyme used
- fragments are the same length/size and have same charge
C4 - by what process do potassium ions normally enter a bacterial cell
- rate of movement/diffusion proportional to concentration gradient
- High concentration of potassium ions inside cell compared to outside
C1 - if you was to draw a peptide bond where the COOH group of one amino acids joins to the NH2 group of another
peptide bond between the carbon and nitrogen molecule
OH from COOH is taken away
H from NH2 is taken away
C1 - Describe how you would use a bio mechanical test to show that a solution contained protein
- Biuret solution
- should turn into a purple colour
C1 - What is the R group attached to in the amino acid structure
- Carbon molecule
C1 - What is the bond between two amino acids
peptide bond
C1 - What does the term hydroxylating refer to
- addition of hydroxyl
- OH group
C6 - Describe the part played by the diaphragm in causing air to enter the lungs during breathing
- diaphragm contracts
- increases thoracic cavity volume of chest
- Decreases thoracic cavity pressure
- allows air to enter
C6 - Table shows the flow of blood to the lungs and to the diaphragm in a seal when it is on land and when it is under water
Explain why the figures in the table would be given per gram of tissue
- allows a comparison in results
- as organs differ in size, larger organs will need more blood
C6 - Calculate the percentage by which blood flow to the lungs is reduced when the seal is swimming under water
Lungs:
On land - 0.88
Under water - 0.52
0.88-0.52 = 0.36
0.36/0.88 x100 = 40.9
C6 - Explain the advantage to a diving seal if blood is continuing to flow to the lungs
- some oxygen still in lungs
- enters the blood
- helps remove carbon dioxide from the blood
C6 - Explain the advantage to a diving seal if a large reduction in blood flow to the diaphragm
- Diaphragm muscles not contracting means that it does not require as much oxygen/glucose
- more blood available for other organs
C3 - What is the process by which the protein thyroglobulin is secreted from the cell
exocytosis
C3 - function of the rough endoplasmic reticulum
- Joining together of amino acids
- protein synthesis
C3 - Explain why the rough endoplasmic reticulum can be seen with an electron microscope and not an optical microscope
- electron microscope has a higher resolution
- uses electrons which have a smaller wavelength
C3 - Explain how the shape of a red blood cell allows it to take up a large amount of oxygen in a short time (2)
- large surface area to volume ratio
- short diffusion pathway
- happens quicker
C1 - Explain what is meant by the proteins tertiary structure
- way in which the whole protein/polypeptide is folded
C1 - What type of chemical reaction is involved in breaking down chitin
hydrolysis
C1 - an unusual protein in found in a grain. its function is to act as an enzyme and break down chitin which is found in the walls of the fungus
breakdown of chitin leads to death by osmosis of fungi attacking the grain
Explain how this happens
- water enters the fungus by osmosis which increases the pressure inside
- cell wall no longer strong enough (cell bursts)
C1 - an unusual protein in found in a grain. its function is to act as an enzyme and break down chitin which is found in the walls of the fungus
Explain why the protein does not break down the cell walls of the job tears plant
- cell wall of plant is not made of chitin its made out of cellulose
- enzyme is specific to chitin so will not break down cellulose
C1 - Explain how heating an enzyme leads to it being denatured
- more kinetic energy
- bonds holding the tertiary structure together break
- Hydrogen, ionic and disulphide bridges
C1 - How can protein engineering make enzymes. more stable and less prone to heat denaturation
- change amino acids
- allowing formation of more hydrogen bonds and disulphide bridges
C1 - an unusual protein in found in a grain. its function is to act as an enzyme and break down chitin which is found in the walls of the fungus
Describe how the sequence of amino acids in part of the protein from Job’s Tears could enable this protein to act as an enzyme inhibitor (6)
- Sequence of amino acids gives the shape
- this is the tertiary structure
- has similar shape to substrate
- competes for active site (competitive)
- fits at site other than the active site (non-competitive)
- distorting active site
- therefore substrate will not fit (active site)
C6 - in each cardiac cycle, the arterial pressure has a maximum value. Explain the link between this maximum value and the events of the cardiac cycle
- corresponds to ventricular systole
C6 - Graph based on artery
Describe two ways in which you would expect blood pressure in a vein to differ from that in an artery (refer to a graph)
- more constant
- little difference between the maximum and minimum values
C6 - Plasma proteins Albumin and Globulin are both not permeable.
Why is it that the water potential of the plasma at the venule end of the capillary is more negative than the water potential at the arteriole end
- plasma proteins are too large to leave the capillary
- therefore water lost and increase in concentration of proteins in the blood plasma
C6 - Although the capillary walls are slightly permeable to haemoglobin molecules, there is no haemoglobin in the tissue fluid
explain what causes the absence of haemoglobin in tissue fluid
- haemoglobin is in the red blood cells
- too large to pass through the membrane of the red blood cells
- red blood cells are to large to pass through the wall
C3 - in what part of the cell does this part of protein synthesis take place
‘Two strands of DNA molecule separate’
nucleus
C8 - Order the following events of protein synthesis
A - tRNA molecules bring specific amino acids to the mRNA molecule
B - mRNA nucleotides join with exposed DNA bases and form a molecule of mRNA
C - The two strands of a DNA molecule separate
D - peptide bonds form between the amino acids
E - the mRNA molecule leaves the nucleus
F - a ribosome attaches to the mRNA molecule
C > B > E > F > A > D