apuntes primer parcial Flashcards

1
Q

cuántos hijos diferente puedes tener de acuerdo al HLA en una pareja monogamica?

A

4

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2
Q

el HLA puede ser utilizado como prueba de paternidad?

A

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3
Q

Cuál es la probabilidad de que un hermano sea 100% identico a ti?

A

25%

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4
Q

variante de un mismo gen

A

Alelo

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5
Q

conjunto de genes

A

haplotipo

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6
Q

De qué manera se hereda el HLA?

A

codominante

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7
Q

Proteinas involucradas en la recombinación

A

RAG 1/2 y HMG 1/2

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8
Q

función RAG 1/2

A

catalizar el rompimiento de una cadena de ADN (secuencia señal) y las unen para dar señales codificadoras

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9
Q

Función HMG 1/2

A

Se introduce en los espaciadores (23bp) y estabilizan la unión de RAG

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10
Q

clases de MHC

A

III

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11
Q

MHCI CLÁSICAS

A

TODAS las células nucleadas

HLA-A
HLA-B
HLA-C

MIC-A
MIC-B
cD4d

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12
Q

MHCI presentes en embarazo

A

E
F
G

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13
Q

MHC-I no clásicas

A

Cd1d
FcRN

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14
Q

interlucinas pro inflamatorias

A

IL-1
IL-6
TNF a

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