Approximate pKa values for functional groups Flashcards
1
Q
carboxylic acid (R-COOH)
A
pKa ~5
2
Q
phenol (Ar-OH)
A
pKa ~10
3
Q
alcohol and water (R-OH)
A
pKa ~15
4
Q
ketone (alpha hydrogen)
A
pKa ~20
5
Q
ester (alpha hydrogen)
A
pKa ~25
6
Q
terminal alkyne
A
pKa ~25
7
Q
amine (R2N-H)
A
pKa ~35
8
Q
alkene (vinylic hydrogen)
A
pKa ~45
9
Q
alkane
A
pKa ~60
10
Q
beta-diketone (alpha H between carbonyls)
A
pKa ~10
11
Q
beta-diester (alpha H between carbonyls)
A
pKa ~15
12
Q
ammonium ion (R3-N+-H)
A
pKa ~10
