Approach to Giddiness Flashcards

1
Q

What are the differentials for vertigo (vestibular)?

A
Central 
- Cerebellar infarct/
haemorrhage
- Vertebrobasilar TIA
- Tumour
- Multiple sclerosis
- Temporal epilepsy

Peripheral (hearing loss)

  • Meniere’s
  • Labyrinthitis

Peripheral (no hearing loss)

  • BPPV
  • Vestibular neuronitis
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2
Q

What are the differentials for faintness (pre- syncope)?

A

Cardiac (arrhythmia)

  • Tacchyarrythmias: supraventricular (AF/AVRT/AVNRT) or ventricular (VT)
  • Bradyarrythmias: sinus bradycardia, heart block, sinus arrest
  • Stokes-Adams attack: syncope due to transient asystole

Cardiac (structural)

  • Left ventricular outflow tract obstruction – aortic stenosis, HCM
  • Right ventricular outflow tract obstruction – pulmonary stenosis

Peripheral Vascular Resistance

  • Vasovagal (3Ps: Postural/prolonged standing, Provoking factors, Prodromal)
  • Drugs (anti-hypertensives)
  • Autonomic Failure (Parkinson’s Disease, DM, B12 deficiency)
  • Reduced vascular tone (septicaemia, adrenal failure/hypocortisolism)

Blood

  • Anemia
  • Hypoglycemia
  • Fluid Loss: diuretics, dehydration, haemorrhage, sepsis
  • Vascular Access Steal syndrome / Dialysis-associated steal syndrome (rare)

Venous Return

  • Pulmonary hypertension
  • Pulmonary emboli
  • Orthostatic hypotension
  • Situational (cough, micturition)
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3
Q

What are the differentials for giddiness that is non- vertiginous and non- faint

A
  • Floatiness/Heaviness
    (Psychosomatic)
  • Unsteadiness (ataxia)
  • Blankness (epileptic)
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4
Q

Clinical features of structural cardiac conditions?

  • ___________ on exertion
  • a/w ____________
  • Family history of __________
  • PMHx: _______________________
  • O/E: murmur
A

Syncope;

SOB, chest pain;

sudden death;

AMI, cardiomyopathy, valvular heart disease, congenital heart disease

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5
Q

Clinical features of arrhythmias?

  • Sudden onset __________ followed by syncope
  • Syncope during _____________
  • Previous MI or cardiac disease
  • Drug history – recent cessation of __________________
A

palpitation

exertion or while supine;

beta-blockers, CCB

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6
Q

Clinical features of vasovagal syncope?

  • Precipitating trigger: _________, _________, __________, _________, _________
  • __________: external pressure to neck or head turning a/w nausea
A

pain, intense emotion, venopuncture, prolonged standing;

Carotid sinus hypersensitivity

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7
Q

Clinical features of postural hypotension?

  • Definition: ______________
  • Light-headedness shortly after standing
  • Drug history – _________________
  • PMH – _____________
A

BP drop >20mmHg systolic or >10mmHg diastolic;

antihypertensives, diuretics;

DM, Parkinson’s

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8
Q

Clinical features of anemia?

  • Symptoms: _________, _________, ________, ___________
  • GI bleed symptoms
  • Diet hx, drug hx – anticoagulation, antiplatelet therapy?
  • O/E: conjunctival pallor
A

chest pain, palpitations, pallor, dyspnoea

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9
Q

Clinical features of hypoglycemia?

A

Symptoms: nausea, sweating, tremors

DM patient on insulin

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10
Q

What is the work up for cardiac causes of dizziness?

A
  • FBC (anemia, raised TW for infection)
  • Blood glucose
  • ECG (for arrythmias), consider Holter if hx suggestive
  • Cardiac Echo if hx suggestive
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11
Q

What are the labyrinth causes of vertigo?

A
  • BPPV
  • Meniere’s Disease
  • Labyrinthitis
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12
Q

What are the 8th nerve causes of vertigo?

A
  • Vestibular neuronitis

* Acoustic Neuroma

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13
Q

What are the brainstem causes of vertigo?

A
  • Vertebrobasilar TIA
  • Intracranial lesion
  • Multiple sclerosis
  • Wernicke’s encephalopathy
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14
Q

What are the cerebellar causes of vertigo?

A

Cerebellar infarct or haemorrhage

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15
Q

What are the temporal lobe causes of vertigo?

A
  • Epilepsy

* Vertiginous Migraine

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16
Q

What are the CNS symptoms and signs seen in patients with central vertigo?

A

CN signs/symptoms

  • Ptosis
  • Diplopia
  • Facial numbness, weakness
  • Dysphagia
  • Dysarthria

Long tract signs (paraesthesia, weakness)

Cerebellar ataxia

Visual loss (hemianopia)

Signs of raised ICP

Headache

17
Q

What is peripheral vertigo associated with?

A
  • may be associated with deafness, tinnitus or fullness of ear
  • nausea and vomiting are usually severe (less reliable)
  • Recent URTI, trauma
18
Q

What is the nature of central nystagmus?

A
  • Changes direction with gaze: fast component to direction of gaze (gaze-evoked nystagmus)
  • Rotatory (pure rotatory, not mixed)
  • Vertical
  • Non-fatigable
19
Q

What are the clinical features of BPPV?

A
  • Vertigo only with postural change, intermittent, recurrent
  • No tinnitus/deafness.
  • Lasts seconds to minutes
20
Q

What are the clinical features of Meniere’s disease?

A
  • Recurrent spontaneous vertigo.
  • Lasts half an hour to several hours
  • a/w tinnitus, deafness, ear fullness
21
Q

What are the clinical features of Labyrinthitis?

A
  • Spontaneous acute vertigo; persistent (days)
  • Nausea/vomiting
  • Hearing loss
  • +/- otalgia/ otorrhea
  • +/- fever
22
Q

What are the clinical features of vestibular neuronitis?

A
  • Spontaneous acute vertigo; persistent (days)
  • Nausea/vomiting
  • No tinnitus/deafness
  • Positive Unterberger test: Patient asked to march in place, rotation towards one side indicative of ipsilateral labyrinthine lesion but is not diagnostic
23
Q

What are the clinical features of vertibrobasilar TIA?

A

CN signs/symptoms

  • Ptosis
  • Diplopia
  • Facial numbness, weakness
  • Dysphagia
  • Dysarthria

Long tract signs (paraesthesia, weakness)

Cerebellar ataxia

Visual loss (hemianopia)

HiNTs – Jerky pursuit, skew deviation, central nystagmus, negative VOR

24
Q

What are the clinical features of intracranial lesion?

A
  • Focal neurological deficit
  • Signs of raised ICP
  • New onset headache
  • Progressive hearing loss
25
Q

What are the clinical features of vertiginous migraine?

A

Five or more episodes of headache with:

  • severe and unilateral orbital, periorbital or temporal pain
  • duration 15-180 min, frequency 1 per 2 days to 8 per day
  • > 1 restlessness/agitation or ipsilateral facial signs
26
Q

What are ototoxic drugs?

A

Gentamicin, Vancomycin, Cisplatin, Frusemide, etc