Applied ANS Flashcards
Where does the ANS arise
- it is a division of the PNS that includes involuntary efferent neurons
what are the divisions of the ANS
- sympathetic
- parasympathetic
- enteric
what is the function of the sympathetic branch and which spinal nerves are involved
- it is important for fight or flight responses and the spinal nerves involved are
- T1 to L2 (Thoracolambar)
What is the function of the parasympathetic branch and which craniosacral nerves are involved
- it is important for rest and digest functions and involves craniosacral nerves
- CN: 3,7,9,10
- Sacral nerves: S2,3&4
which nerve supplies most of parasympathetic outflow
- vagus nerve [CN X]
what are the three groups of neurotransmitters
- Acetylcholine
- Norepinephrine/Epinephrine
- Non-Ach/Non-Adrenergic
where do you find Ach neurotransmitters
- preganglionic
- postganglionic parasympathetic
- postganglionic parasympathetic in sweat glands
where do you find Norepinephrine/Epinephrine neurotransmitters
- postganglionic sympathetic
what are 6 examples of non-Ach/Non-Adrenergic neurotransmitters
- serotonin
- GABA
- histamine
- dopamine
- nitric oxide
- 5-hydroxytryptophan
what are the basic steps and sites for drug action
- Synthesis of a transmitter
- Storage of a transmitter
- Release of a transmitter
- Interaction of a transmitter with receptor on effector cells
- Removal/Degradation/Recycling of transmitter
what are the two cholinergic receptors and the receptor types
- Nicotinic - Nn and Nm
- Muscarinic - M1 to M5
what are the two types of Adrenergic Receptors and their types
- Alpha - alpha 1 and alpha 2
- Beta - beta 1 and beta 2
where are M1 receptors located
- CNS
- ganglia
where are M2 receptors located
- heart
- nerves
- smooth muscle
where are M3 receptors located
- glands
- smooth muscle
- endothelium
