applictaion of genetics human genome project Flashcards
1
Q
definition of human genome
A
sequencing nucleotides in human genome
2
Q
aims of HGP
A
- determine base sequence of human dna
- address medical social and legal issues that may arise
3
Q
How did genomes used to be sequenced
A
using sanger sequencing
sequences small sections of dna at a time
takes long
now use NGS much faster
4
Q
100k genome project
A
set up to use NGS to sequence 100000 genomes from nhs patients with cancer or a rare disease
5
Q
moral and ethical concerns of human genome project
A
- social discrimination
- misuse of data
- company may try to make financial profit from using dna sequence without permission
6
Q
pharmocogenetics
A
how an individuals genetic inheritance affects the body’s response to drugs
7
Q
benefits of genetic testing
A
- warn people at risks to take precautions / make lifestyle changes
- plan medical provision
- that they may have children with the genetic disorder
- make it easier to develop way of treating genetic deficiencies
8
Q
disadvantages of genetic testing
A
- people under pressure for abortions (embryonic screening)
- may lead to other thi ally questionable developments such as designer babies
- stres and anxiety
- data protection- who has access to genetic information
9
Q
how was crispr cas 9 used in mosquitos?
A
- mosquito eggs modified with addition of gene
- allows them to synthesise antibody against plasmodium
- when plasmodium taken in by mosquito when feeding from an infected person
- plasmodium doesn’t survive in mosquito
