APPLICATIONS OF TOXICOLOGY Flashcards

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1
Q

Which of the following is most commonly used as a drug of se**l assault?

A

Ethanol

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2
Q

Analytic and forensic toxicology

A
  • Medical examiners and coroners are most important in determining cause of death.
  • Tissues and body fluids are vital in forensic toxicology.
  • Forensic toxicology is used for purposes of the law.
  • Chapuis first characterized a system for classifying toxic agents.
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3
Q

criterias routinely used to check for adulteration of drug urine analysis?

A
  • pH
  • color
  • specific gravity.
  • creatinine.
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4
Q

Which blood alcohol concentration (BAC) is most commonly used as the statutory definition of DUI?

A

0.08

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5
Q

Benzodiazepines

A

GC/MS.

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6
Q

Ibuprofen

A

TLC/HPLC.

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7
Q

Aphetamines

A

immunoassays.

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8
Q

barbiturates

A

GC/immunoassays.

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9
Q

serum used during toxicology testing?

A
  • Ethanol
  • aspirin.
  • barbiturates.
  • ibuprofen.
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10
Q

Which of the following is LEAST important in determining variability in response to drug therapy?

A

BMI

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11
Q

steady state

A
  • Steady-state concentrations are proportional to the dose/dosage interval.
  • Steady state is attained after approximately four half-lives.
  • The steady-state concentrations are proportional to F/Cl.
  • Monitoring of steady-state drug concentration assumes that an effective concentration is present.
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12
Q

indirect method of measuring a chemical or its metabolite?

A

hemoglobin adduct detection.

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13
Q

analytic/forensic toxicology

A

Toxicologists can play an important role in courtroom testimonies

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