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Biochemistry 141 > Application of enzyme inhibitors in medicine > Flashcards

Application of enzyme inhibitors in medicine Flashcards

1
Q

Aspirin

A

Cyclooxygenase

  • Inhibits synthesis PG & TX.
  • Used to Treat Pain & Clotting.
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2
Q

Penicillin

A

Transpeptidase

  • Inhibits synthesis of Cells Wall.
  • Used to Treat Bacterial Infection.
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3
Q

Sulfa drugs

Sulfonamides

A

Dihydropteroate Synthetase

  • Inhibits synthesis of B9 Folate.
  • It is an analogue of PABA.
  • Used to Treat Bacterial Infection.
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4
Q

Isoniazid

A

NAD Synthetase

  • Inhibits synthesis of NAD.
  • It is an analogue of Nicotinamide.
  • Used to Treat Bacterial Infection.
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5
Q

Ethanol

A

Alcohol Dehydrogenase

  • Inhibits synthesis of Formaldehyde.
  • it is an analogue of Methanol.
  • Used to Treat Methanol Poisoning.
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6
Q

Ethanol

A

Alcohol Dehydrogenase

  • Inhibits synthesis of Oxalic acid.
  • It is an analogue of Ethylene glycol.
  • Used to treat Ethylene Glycol Poising
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7
Q

Methotrexate

A

DHF Reductase

  • Inhibits synthesis of THF.
  • As it is an analogue of DHF.
  • Used as Chemotherapy treats Cancer.
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8
Q

Allopurinol

A

Xanthine Oxidase

  • Inhibits synthesis of Uric Acid.
  • It is an analogue of Xanthine.
  • Used to treat Gout Hyperuricemia.
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9
Q

Transpeptidase

A

Penicillin Irreversible

Suicidal Inhibitor

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10
Q

NAD Synthetase

A

Isoniazid

Reversible Competitive Inhibitor

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11
Q

Alcohol Dehydrogenase

A

Ethanol

Reversible Competitive Inhibitor

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12
Q

Xanthine Oxidase

A

Allopurinol Reversible

Competitive inhibitor

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13
Q

Cyclooxygenase

A

Aspirin Irreversible

Suicidal Inhibitor

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14
Q

Dihydropteroate

Synthetase

A 
Sulfa drugs (Sulfonamides)
Reversible Competitive Inhibitor
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15
Q

DHF Reductase

A

Methotrexate Reversible

Competitive Inhibitor

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16
Q
  • Inhibits synthesis PG & TX.

- Used to Treat Pain & Clotting.

17
Q
  • Inhibits synthesis of B9 Folate.
  • It is an analogue of PABA.
  • Used to Treat Bacterial Infection.
A

Sulfa drugs

18
Q
  • Inhibits synthesis of Formaldehyde.
  • it is an analogue of Methanol.
  • Used to Treat Methanol Poisoning.
19
Q
  • Inhibits synthesis of THF.
  • As it is an analogue of DHF.
  • Used as Chemotherapy treats Cancer.
A

Methotrexate

20
Q
  • Inhibits synthesis of Cells Wall.

- Used to Treat Bacterial Infection.

A

Penicillin

21
Q
  • Inhibits synthesis of NAD.
  • It is an analogue of Nicotinamide.
  • Used to Treat Bacterial Infection.
22
Q
  • Inhibits synthesis of Oxalic acid.
  • It is an analogue of Ethylene glycol.
  • Used to treat Ethylene Glycol Poising
23
Q
  • Inhibits synthesis of Uric Acid.
  • It is an analogue of Xanthine.
  • Used to treat Gout Hyperuricemia.
A

Allopurinol

Biochemistry 141 (17 decks)

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