Application of enzyme inhibitors In Medicine

Question 1

Aspirin

Answer 1

Inhibit Cyclooxygenase
Inhibits synthesis PG and TX
Used to treat paint and clotting

Question 2

Penicillin

Answer 2

Inhibits Transpeptidase
inhibit synthesis of cells well
Used to treat bacterial infection

Question 3

Sulfa drugs (sulfonamides)

Answer 3

Inhibits dihydroproteroate synthestase
Inhibits synthesis of B9 folate
It is an analogue of PABA
Used to treat bacterial infection

Question 4

Isoniazid

Answer 4

Inhibits synthesis of NAD
It is an analogue Of nicotinamide
Used to treat bacterial infection

Question 5

Ethanol

Answer 5

Inhibits alcohol dehydrogenase
Inhibit synthesis of formaldehyde
It’s an analogy of methanol
Used to treat methanol poisoning(causes blindness)

Question 6

Ethanol 2

Answer 6

Inhibits Alcohol dehydrogenase
Inhibits synthesis of oxalic acid
It is an analogue of ethylene glycol  used to treat ethylene glycol poisoning(in children it’s causes renal stones)

Question 7

Methotrexate

Answer 7

Inhibits DHF reductase
Inhibit synthesis of THF
As it is an analogue of the DHF
Used as chemotherapy treats cancer

Question 8

Allopurinol

Answer 8

Inhibits Xanthine oxidase
Inhibit synthesis of uric acid
It is an analogue of xanthine
Used to treat gout hyperuricemia