Appendix K TEMS Medication Information Flashcards
Adenosine (Adenocard)
A chemical hyperpolarization agent and diagnostic aid for Narrow-Complex Tachycardias
Adenosine (Adenocard) How many vials in the drug box? 6 mg/ 2 mL vial
3 Vials in the Drug Box (Red metal box secured in unit) 3 x 6 mg/ 2 mL = 18 mg/ 6 mL
Indications for use of Adenosine (Adenocard)
Symptomatic Paroxysmal Supraventricular Tachycardia (SVT)
Functions and Characteristics of Adenosine (Adenocard)
- Adenosine induces a transient heart block in the AV node, and may be able to break certain forms of SVT, converting to normal conduction (i.e., Sinus Rhythm, or Sinus Tachycardia) - Fast rhythms of the heart that are confined to the atria (e.g., atrial fibrillation, atrial flutter) or ventricles (e.g., monomorphic ventricular tachycardia) and do not involve the AV node as part of the re-entrant circuit are not typically converted [Ventricular response rate is temporarily slowed with adenosine in such cases and may be of use as a diagnostic aid] - Remarkably short half life - Must be administered fast IV push with ready bolus flush without delay - Use of a 3-way stopcock may facilitate delivery - Will not affect atrial fibrillation, atrial flutter, or ventricular tachycardia
Contraindications for use of Adenosine (Adenocard)
- Second or third degree AV block (except in patients with a functioning pacemaker) - Sick Sinus Syndrome (except in patients with a functioning pacemaker) - Poison induced tachycardia - Patients with known hypersensitivity to Adenosine
Precautions of Adenosine (Adenocard)
- The effects of Adenosine (Adenocard) are antagonized by methylxanthines such as caffeine and theophylline, so larger doses of Adenosine (Adenocard) may be required to by effective - Use with caution in patients with asthma
Adenosine (Adenocard) Dosage
Adult Dosage - Initial 6 mg rapid IV push with immediate 10 mL Normal Saline flush, if desired effect not obtained within 1-2 minutes, then consider repeat dosage of 12 mg rapid IV push Initial Dose - (6 mg/2 mL - Draw up 1 vial) Repeated Dose - (12 mg/4 mL - Draw up 2 vials) *At that point you are out of vials (3 Vials/Drug Box)* Pediatric Dosage - Initial dosage 0.1 mg/kg rapid IV push with 10 mL Normal Saline flush (not to exceed 6 mg rapid IV push), if desired effect not obtained within 1-2 minutes, then consider 0.2 mg/kg (not to exceed 12 mg rapid IV push)
Albuterol Sulfate (Proventil)
A sympathomimetic for bronchial dilation or potassium transport agent in Crush Syndrome Used for Allergic/Anaphylactic Reaction, Difficulty Breathing, Crush Syndrome, & Dialysis-Renal Failure
How is Albuterol Sulfate (Proventil) found and packaged in the Red Drug Box?
2.5 mg bullet x 6 (3 bullets in the Drug Box and 3 bullets in the IV Box) *Blue Packages mixed with 3 mL Normal Saline*
Functions of Albuterol
- Albuterol produces bronchodilation by relaxing bronchial smooth muscle through beta-2 receptor stimulation. In addition, it can help drive potassium back in to cells afflicted by Crush Syndrome injuries, combating hyperkalemia-associated complications - For severe distress and/or breathing difficulty which has not responded to home treatments, a cocktail of 2.5 mg Albuterol (blue package) and 0.5 mg Atrovent (green package) may be a more appropriate first-line treatment (COMBI-Tx) - May commonly induce tachycardia and tremor(s) - Should be given any time a CHF patient is wheezing - Should be given on a continuous basis for Crush - HHN flow rate should be 4-6 L/minute or 8-10 L/minute when utilizing a mask (NRB) - May require coaching to properly administer to some patients (Respiratory Distress w/ bronchoconstriction pts.)
Indications for use of Albuterol Sulfate (Proventil)
- Asthma, status asthmaticus - Crush injury - Bronchospasm in patients with reversible obstructive airway disease
Contraindications for use of Albuterol Sulfate (Proventil)
- Symptomatic tachycardia - Any known hypersensitivity to the drug
Precautions of Albuterol Sulfate (Proventil)
- Patients with cardiovascular disorders (coronary insufficiency, arrhythmias, hypertension, etc.) - Convulsive disorders and diabetes - Blood pressure, pulse should be monitored (Increases HR = Increases BP due to Increased CO)
Albuterol Sulfate (Proventil) Dosage
- Adult Breathing Difficulty 2.5 mg HHN(*) - Adult Allergic Reaction/Anaphylaxis 2.5 mg HHN - Crush Syndrome 2.5 mg HHN continuous treatments - Pediatric Breathing Difficulty 2.5 mg HHN - Pediatric Allergic Reaction/Anaphylaxis 2.5 mg HHN - Renal Failure 2.5 mg HHN continuous treatments HHN* = Hand Held Nebulizer
Amiodarone (Cordarone)
A dysrhythmic for wide-complex tachycardias and ventricular fibrillation (& ROSC)
How is Amiodarone (Cordarone) packaged in the drug box?
150 mg/3 mL vial x 3 (Drug Box)
Total amount of drug 450 mg/9 mL
FYI Amiodarone
- A complex dysrhythmic, its action is not entirely understood, though is thought to involve prolonging the action of potential duration, prolonging the refractory period, or interacting with K+ channels.
- Never Given IV push to a perfusing rhythm, and never given via ETT
- Remarkably long half-life (25-100 days, average 58 days) within the body
- Viscous, and easily foams when draws up rapidly with smaller gauge needles
- Flush IV line thoroughly when administered in the same IV line as furosemide, heparin or sodium bicarbonate
- Use Zofran with caution due risk of dysrhythmias due to prolonged Q-T intervals
Indications for use of Amiodarone (Cordarone)
- Ventricular fibrillation
- Pulseless ventricular tachycardia
- Ventricular tachycardia with a pulse
Contraindications for use of Amiodarone (Cordarone)
- Hemodynamically significant bradycardia
- 2nd and 3rd degree heart blocks unless patient has a functioning pacemaker
- Any known hypersensitivity to the drug
Precautions for use of Amiodarone (Cordarone)
- Use with caution with patients that are currently taking
- Beta blockers
- Calcium Channel Blockers
- Anticoagulants
- Heart Failure
Amiodarone (Cordarone) Dosage
- Wide Complex Tachycardia
- 150 mg in 100 mL NS given over 10 minutes
- Ventricular Fibrillation
- 1st Dose 300 mg rapid IVP/Bolus
- 2nd Dose 150 mg rapid IVP/Bolus
- Pediatric Wide Complex Tachycardia
- 5 mg/kg over 20 minutes
- Pediatric Ventricular Fibrillation
- 5 mg/kg over 10 minutes
Aspirin (Acetylsalicylic acid, ASA)
An antiplatelet for suspected cardiac ischemia and barotrauma
(Chest Pain, Acute Myocardial Infarction, & Acute Coronary Syndrome)