Apnoea and respiratory failure Flashcards
What are the findings in type 1 respiratory failure?
- PaO2 = ↓ + PaCO2 = normal or low
* Characterised by Hypoxaemia without hypercapnia
What are the findings in type 2 respiratory failure?
- PaO2 = ↓ + PaCO2 ↑
* Characterised by hypoxaemia with hypercapnia
Which type of respiratory failure is worse?
Type 2
What is the definition of respiratory failure?
pulmonary gas exchange is sufficiently impaired so as to cause Hypoxaemia +/- Hypercapnia
What causes Type 1 respiratory failure?
Ventilation perfusion mismatch or right to left shunt
What causes Type 2 respiratory failure?
Aveolar hypoventilation
What is chronic respiratory failure?
- Chronic respiratory failure develops over several days or longer, allowing time for renal compensation and an increase in bicarbonate concentration.
- Therefore, the pH usually is only slightly decreased.
Name 9 causes of type 1 respiratory failure?
- Pneumonia
- Pulmonary oedema
- PE
- Asthma → acute severe
- Emphysema
- Pulmonary fibrosis
- ARDS
- Lung fibrois
- Right to left heart shunt
Name 4 main causes of type 2 respiratory failure?
• Pulmonary disease:
♦ Asthma - Life threatening, sever acute ♦ COPD ♦ Pneumonia ♦ End stage pulmonary fibrosis ♦ Obstructive sleep apnoea
• Reduced respiratory drive:
♦ Sedative drugs
♦ CNS tumour
♦ trauma
• Neuromuscular disease:
♦ Cervical cord lesion
♦ Diaphragmatic paralysis
♦ Polio, GB, MG
• Thoracic wall disease:
♦ Flail chest
♦ Kyphoscoliosis
Which 3 cervical nerves make the diaphragm work?
• C3, C4, C5 → keep the diaphragm alive
Where is the breathing regulator?
Medulla oblongata
What is the first thing you do in the treatment of Repsiratory failure?
Treat the underlying cause.
What is CPAP?
• Continuous Positive Airway Pressure
What is BiPAP?
• Bi-phasic Positive Airway Pressure
What is IPPV?
• Intermittent Positive Pressure ventilation