Apnea (Strauss) Flashcards
What is key to understanding and treating Obstructive Sleep apnea?
It can be fatal if misdiagnosed or mistreated
Sleep related deaths most commonly occure between what hours?
Between 2-4 pm and 4-6 am. Matches circadian sleep pattern
No sleep for 24 hrs produces same cognitive impairment when operating an automobile as what blood alcohol level?
0.10%
What is the sound associated with the vibration of some anatomical area within the airway caused by a partial airway obstruction and pharyngeal flow limitation and is generally benign?
Snoring
Does snoring cause arousal during inspiration?
No
Snoring can be how loud?
69-80 dB, the same as a 737 at 100 ft
What is the pathophysiology of snoring and sleep related breathing disorders (SRBD)?
Tonus is decreased in airway with sleep so airway lumen decreases in diameter, which means the same volume of air must move through there faster, causing turbulence
The greater the speed of a gas or liquid the more / less pressure it exerts?
Less pressure it exerts (Bernouli’s Principle)
Why is Bernoulli’s principle important to snoring?
Because air going down the trachea is moving faster than air in the soft palate, the mouth is lower pressure due to speed, and the area above the palate is high pressure. This pressure differential will cause the soft palate to raise toward the area of high pressue and a snore is produced.
What is the danger with a small airway lumen and increased air speed?
Increased airspeed could cause the lumen to close completely
Is there a definite delineation between snoring and obstructive sleep apnea or is it a continuum?
Continuum
What are 9 complications of Obstructive Sleep apnea?
- Hypoxemia
- Hypercarbia
- Polycythemia
- Hypertension
- Depression
- Impotence
- Cerebrovascular accident (CVA) / stroke
- Arrythmias
- Sudden death
What is the link of hypoxemia and hypercarbia in obstructive sleep apnea?
Hypoxemia is low blood oxygen which would imply Hypercarbia which is high blood carbon dioxide
Why is there polycythemia in OSA?
Body increase red blood cells to compensate for low blood oxygen
What is a risk associated with polycythemia?
The blood is thicker due to increased red blood cells
Are snoring and OSA the same pathophysiology?
Yes. Airway constriction, speed of airflow, and airway collapse
What are 3 apnea patterns?
- Obstructive
- Central
- Mixed
What are 2 subtypes of obstructive apnea?
- Apnea
2. Hypopnea
Of the 2 subtypes of Obstructive apnea, which one is the most common type of OSA?
Obstructive apnea
In what type of apnea does airflow stops for longer than 10 secs due to closure of airway by obstruction, while the chest wall inspiratory effore is normal?
Obstructive apnea
What is the drop in oxygen saturation in obstructive apnea?
More than 2% drop
What does obstructive apnea terminate with?
Arousal (brain wakes body up to breath)
What is the least common type of apnea?
Central
What is the cause and duration of airflow stop in Central Apnea?
Lack of inspiratory effort due to lack of brain effort. Airflow stops for longer than 10 seconds
How does Central Apnea terminate?
Arousal from sleep
Will a splint or surgery fix central apnea?
No
How will mixed apnea present?
Central (brain) effect on ventilatory effort, but even after central effort begins obstruction prevents ventilation (airway collapse)
How does Mixed Apnea terminate?
Arousal
Obstructive Hypopnea, while having diminished airflow, will have continuous flow at what percentage?
Less than 66%
What is the drop in oxygen saturation in obstructive hypopnea?
More than a 2% drop in oxygen (same as obstructive apnea)
How does obstructive hypopnea terminate?
Arousal
What will happen to the ventilatory effort in obstructive hypopnea?
Will be unchanged or increased
What is the term for when sleep terminates with arousal due to some respiratory abnormality, but the events do not meet the criteria for obstructive apnea or obstructive hypopnea?
Respiratory effort related arousal (RERA)
Respiratory Effort Related Arousal (RERA) is associated with what other airway syndrome?
Upper Airway Resistant Syndrome (UARS)
Upper Airway Resistance Syndrome (UARS) has what symptoms?
Snoring symptoms and Excessive Daytime Sleepiness (EDS)
Why is Upper Airway Resistance Syndrome (UARS) often misdiagnosed?
Not seen on the polysomnography (PSG), there is no brain activity show it
Is pediatric OSA the same as adult OSA?
No