Aphakia Flashcards
Visually significant infantile cataracts are responsible for what percentage of childhood blindness worldwide?
5-20%
60-65% of infantile cataracts have an identifiable cause; what are the genetic systemic conditions that can cause them?
there are 4 of them
Galactosemia, Wilson’s Disease, Lowe’s Syndrome and Juvenile Diabetes
What type of opacities are seen in galactosemia?
GALT gene mutation results in GALT NZ deficiency
galactose related chemicals accumulated in various organs
Oil droplet
infants also have jaundice
What are ocular manifestations of Wilson’s disease?
Kayser-Fleischer ring, sunflower cataract
Lowe’s syndrome is the inability to regulate what?
essential minerals, salts and water
What type of cataract is caused by Juvenile diabetes?
anterior and posterior subcapsular white spots or snowflake-like opacity
large fluctuations in glucose causes changes in lens osmotic pressure
Which location of a juvenile cataract is the most devastating?
posterior pole
closest to nodal point
Which cataract has the least effect on VA?
anterior pole
Prognosis declines if surgical removal of crystalline lens occurs after which age?
2 years
When is the risk of aphakic glaucoma highest?
When cataract is removed before 4 weeks of age
When is the best time to remove a congenital cataract for the best visual prognosis?
4-6 weeks of age
What are optical correction options for aphakic children?
epikeratophakia (uncommon); spectacles; IOLs; contact lenses
When can IOLs be considered?
After 2 years of age
What types of contact lenses can be used for aphakia?
corneal GPs, Scleral lenses, B&L Silsoft Lens; custom Soft contact lenses (flexlens aphakic lens)
Which CL option is approved by the FDA as 30-day extended wear lens for aphakia?
Silsoft
