AP Flashcards
Renal Medullary Carcinoma in who
Sickle cell trait
Type A> thymoma
> > > > > > > spindled
Glomus IHC
SMA, Caldesmon
Clear cell sarcoma
HMB45 stronger than S100
MelanA, MiTF
ground glass bone Xray
Fibrous Dysplasia
Rheumatoid nodule
geographically demarcated zones of fibrinoid necrosis surrounded by palisading histiocytes
Chrondroblastoma
chicken wire calcs
plasmacytoid chondroblasts
giant cells
osteochondroma has connection/ maturation into the______________
medulla
periosteoal chrondoroma vs osteochondroma
periosteoal chrondoroma contained within the periosteum/cortex, no maturation or connection to medulla
angiolipoma location
volar forearm
Soft tissue tumors with pain
angio lipoma
angio leiomyoma
Myxoma syndromes?
M–> MM
Mazabraud syndrome
McCune-Albright syndrome
Schwannoma
dilated vessels with hyalinized, thick walls
PMT
reminiscent of hemangiopericytoma (HPC), but additionally it may contain areas of cartilaginous metaplasia with “grungy” calcification, adipose and fibrous tissue, and osteoclastlike multinucleated giant cells
Cellular angiofibroma
vulvovaginal, inguinal, and paratesticular regions
milk line
just like mammry type myofibroblastoma
ER PR pos
One consistent UPH marker
vimentin
UPS vs MFS
UPF = Vimentin MFS = vimentin + SMA
NF stains
s100 (schwann)
NF (axons)
34 (stromal)
EMA/GLUT1 (peineureum)
Myofibroma
subcut
ZONAL on low
uveal melanoma and blue nevus share what?
same mutation - GNAQ
Pemphigus Vulgaris
PV–> V3 –> desmogelin 3
Pemphigus follieaceous
floats to the top so is #1 –> Desmogelin 1
differentiate b/w aggressive angiomyxoma, cellular angiofibroma and angiomyofibroblastoma
aggressive angiomyxoma = has muscular vessels = desmin, SMA pos
cellular angiofibroma = thinner vessels = starts with angio = CD34 pos
angiomyofibroblastoma = Desmin pos, SMA neg
