AP Flashcards

1
Q

Renal Medullary Carcinoma in who

A

Sickle cell trait

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2
Q

Type A> thymoma

A

> > > > > > > spindled

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3
Q

Glomus IHC

A

SMA, Caldesmon

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4
Q

Clear cell sarcoma

A

HMB45 stronger than S100

MelanA, MiTF

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5
Q

ground glass bone Xray

A

Fibrous Dysplasia

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6
Q

Rheumatoid nodule

A

geographically demarcated zones of fibrinoid necrosis surrounded by palisading histiocytes

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7
Q

Chrondroblastoma

A

chicken wire calcs
plasmacytoid chondroblasts
giant cells

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8
Q

osteochondroma has connection/ maturation into the______________

A

medulla

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9
Q

periosteoal chrondoroma vs osteochondroma

A

periosteoal chrondoroma contained within the periosteum/cortex, no maturation or connection to medulla

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10
Q

angiolipoma location

A

volar forearm

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11
Q

Soft tissue tumors with pain

A

angio lipoma

angio leiomyoma

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12
Q

Myxoma syndromes?

A

M–> MM
Mazabraud syndrome
McCune-Albright syndrome

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13
Q

Schwannoma

A

dilated vessels with hyalinized, thick walls

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14
Q

PMT

A

reminiscent of hemangiopericytoma (HPC), but additionally it may contain areas of cartilaginous metaplasia with “grungy” calcification, adipose and fibrous tissue, and osteoclastlike multinucleated giant cells

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15
Q

Cellular angiofibroma

A

vulvovaginal, inguinal, and paratesticular regions

milk line

just like mammry type myofibroblastoma

ER PR pos

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16
Q

One consistent UPH marker

A

vimentin

17
Q

UPS vs MFS

A
UPF = Vimentin
MFS = vimentin + SMA
18
Q

NF stains

A

s100 (schwann)
NF (axons)
34 (stromal)
EMA/GLUT1 (peineureum)

19
Q

Myofibroma

A

subcut

ZONAL on low

20
Q

uveal melanoma and blue nevus share what?

A

same mutation - GNAQ

21
Q

Pemphigus Vulgaris

A

PV–> V3 –> desmogelin 3

22
Q

Pemphigus follieaceous

A

floats to the top so is #1 –> Desmogelin 1

23
Q

differentiate b/w aggressive angiomyxoma, cellular angiofibroma and angiomyofibroblastoma

A

aggressive angiomyxoma = has muscular vessels = desmin, SMA pos

cellular angiofibroma = thinner vessels = starts with angio = CD34 pos

angiomyofibroblastoma = Desmin pos, SMA neg